A peculiar form of hereditary congenital cataract / by E. Nettleship and F. Menteith Ogilvie.

  • Nettleship, Edward, 1845-1913.
Date:
[1906?]
Catalogue details

Licence: In copyright

Credit: A peculiar form of hereditary congenital cataract / by E. Nettleship and F. Menteith Ogilvie. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    2 ill 1895, and probably a fouvtli (Y, II) in 1896. But the greater miniber have been discovered by Mr. Ogilvie during the last few months. U’e have lo thank Mr. George Mackay, of Edinburgh, and Mr. Hill Griffith, of Manchester, for their kindness in examining two small groups of Coppocks living near those cities ; but none of these, nine in number, are affected. Through the kindness of Mr. Doyne and Mr. Ogilvie I have had the opportunity of seeing several of the cases at the Oxford Eye Hospital, but my share in the present paper has consisted in little more than suggesting that the family history was worth fully working out. The whole race seems healthy, is fairly prolific and intelligent, and has held its own and multiplied largely without, in the main, spreading far afield. Thus of the present ))opulation of the village of lleadington Quarry, numbering 1500, at least 300 are descended from the original John Copjiock, and others are scattered in neigh- bouring villages. We were therefore ’j)repared to find that consanguineous marriage had been common, and felt some liope that the history might throw light upon the (juestion whether consanguinity is in itself a cause of degeneracies. This hope has been but very partially realised, for only five instances of cousin-marriage have been ‘proved in the entire pedigree, and they throw no decided light on the general question just raised. In regard to the influence of consanguinity in camsing the peculiar cataract itself, a glance at Fig. 25, which is a condensed combination of the pedigrees drawn uj) by Mr. Ogilvie and the vicar res])ectively, will show that the family cataract has been found hitherto (as already mentioned) only in one branch of the stock ; that although in three of the four consanguineous marriages {h, c and d) one of the cousins was a member of that branch, we find that the cataract apjieared in the offspring of only one of the cousin-marriages, and that in that case one of the 2narents had it; in the other cousin-marriages, wlierc all the parents were free, their children were free also.