The measurement of linkage in heredity / by K. Mather.

  • Mather, Kenneth, 1911-1990.
Date:
[1938]
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: The measurement of linkage in heredity / by K. Mather. Source: Wellcome Collection.

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    CHAPTER II TWO CLASS SEGREGATIONS 3. deviation and heterogeneity ANALYSIS of the single factor segregations is the first consideration not only because of the interest which may attach to them themselves, but also because the subsequent treatment of the data will depend to some extent on the nature of these single factor ratios. Two questions may be asked about the segregation of a single factor : (a) Is it in keeping with some expected ratio, e.g. 3:1 or 1:1? (b) Are all the families in agreement in showing the same result, i.e. are the data homogeneous ? The answers to both questions are provided by suitable tests of significance. 4. the use of the standard error One of the most popular tests of significance used in detecting deviations from expected ratios is that based on the standard error, discussed in the previous chapter. The standard error of a binomial distri bution, ( X + y) n is given by the formula This is the standard error appropriate to testing the agreement of that observed proportion of the family which falls into one class with its expected value 13