Observations on medicinal pepsin and artificial digestion / by G.F. Dowdeswell.

  • Dowdeswell, G.F.
Date:
[1880]
Catalogue details

Licence: Public Domain Mark

Credit: Observations on medicinal pepsin and artificial digestion / by G.F. Dowdeswell. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    gradually increased, till, if practicable, it was found capable of effecting the solution. The results of these examinations are given in Table II., which also represents a series of experiments made simultaneously and repeated more than once, with the quantity therein specified of each preparation; an isolated experiment was seldom made, and never relied upon to establish any conclusion; the different preparations were always tried simultaneously under the same conditions, nearly always in duplicate, and the experiment repeated several times. Table I. Showing the result of the action in four hours at 100° F. of different preparations of Pepsin, in the quantity specified, on 100 grs. of coagulated egg-albumen, in 1 oz. of dilute Hydrochloric Acid, 1 per cent. Preparation. Reaction. Quantity used. Result. 1 Glycerine of Pepsin (Bullock) Acid f- 3i- All dissolved. 2 Liquor Pepticus (Benger) A. . i f f.5i. Not dissolved. ,, ,, b. . f. 3 i- All dissolved. 3 Pepsin Wine (Morson) . . ft f- 5 i- Not dissolved. 4 Pepsin Essenz (Liebreich) ft f. 3 i. ft ft PepsinaPorci B. P. (Bullock) f t f. 3 iii. ft ft All dissolved. 5 t f grs. ii. 6 l Pepsin' B. P. ex ovibus (Wright ) ( and Layman) .... ) f Faintly 1 { Acid j grs. ii. Not dissolved. 1 i ii l Pepsin B. P. ex ovibus (Hop- ) ( kins and Williams) . . . ) ft grs. y. All dissolved. 7 11 grs. ii. Not dissolved. t f Neutral grs. y. All dissolved. 8 Saccharated Pepsin (Finzelberg) grs. iii. Not dissolved. it ii if Starch Pepsin (Bouda|t) . . Pepsin Porei B. P. (Morson). i t Acid grs. vi. All dissolved. 9 grs. v. grs. x. Not dissolved. All dissolved. 10 i » grs. ii. Not dissolved. it f fm ft Starch Pepsin (Morson) . . t f grs. iv. All dissolved. 11 ft Neutral grs. x. ft tf Not dissolved. 12 Saccharated Pepsin (Wyeth) . ft ' ft ft Lactopeptine grs. ii. grs. v. i r Acid ii ft 13 grs. x. t t ft 11 ft Faintly Acid grs. xy. ft ft 14 Ingluvin | grs. v. tf tt Compressed Peptonic Tablet ) (Wyeth) \ 1 t grs. x. ft it 15 Acid 1 Tablet. ft ft The. above gives the minimum and maximum doses directed of each preparation. No. 2 B was a second sample received of the same preparation, found to be much more active than the first (a) ; subsequent experiments were made with the second sample (b). Nos. $and 9 appeared to be exactly the same make. 5 7