Anatomy, physiology, pathology, dictionary / edited by W.A. Evans, Adolph Gehrmann, William Healy.

Date:
1906
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Licence: In copyright

Credit: Anatomy, physiology, pathology, dictionary / edited by W.A. Evans, Adolph Gehrmann, William Healy. Source: Wellcome Collection.

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    pneumococci can remain in the blood he is not prepared to state. He thinks that crisis is due to something other than disappearance of pneumococci from the blood. Experimental Arteriosclerosis. Bernhard Fischer1 ex- perimented with adrenalin and digalin in the production of arteriosclerosis. He found that these agents produced changes in a two-fold way. They poisoned local areas, producing death of some histologic elements and over- growth of others, and secondly, they operated by increasing blood pressure. The media gave way and a growth of new tissue occurred in the media. It did not invade the intima. The amount of sound tissue outside it determined whether it was to be a yellowish curdy raised placque in the lumen of the vessel or was to originate an aneurysmal area. Fischer did not find that a slowing of the current of blood due to dilation was followed by a thickening of the wall, as Thomas had claimed. Such a growth of fibrous tissue was always inflammatory, never compensa- tory. POISONING. Chronic Acetanilid Poisoning. Herrick and Irons2 3 characterize the symptoms of chronic acetanilid poisoning as follows: Cyanosis, that may be extreme; more or less dyspnea and general weakness; dark colored urine that contains paramidophenol and an increased amount of ethe- rial sulphates; anemia of the secondary type, with degen- erated and nucleated red blood corpuscles; methemoglobin may be present in the blood and in the urine; dizziness, syncope, tinnitus and palpitation may be marked when the anemia is advanced. The spleen is often enlarged. Ano- rexia, nausea, vomiting, and diarrhea may occur. Nervous- ness and restlessness are aggravated when the drug is with- drawn. Intravenous Injection of Nicotin. Adler and HenseP injected rabbits intravenously with a solution of l-\ milli- grams of pure nicotin in water daily for one to two months. They got atheroma lesions in the aorta. The lesions begin as a degeneration of the muscle fibers next (1) Deutsche med, Woehenschr., vol. XXXI, 1905. (2) Jour. Am. Med. Assoc., Feb. 3, 1906. (3) Jour. Med. Research, September, 1906.