The treatment of syphilis with subcutaneous sublimate injections / by Dr. George Lewin ; translated by Carl Proegler and E.H. Gale.

  • Lewin, Georg Richard, 1820-1896.
Date:
1872
Catalogue details

Licence: Public Domain Mark

Credit: The treatment of syphilis with subcutaneous sublimate injections / by Dr. George Lewin ; translated by Carl Proegler and E.H. Gale. Source: Wellcome Collection.

Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.

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    giving -^ gr. pro die. The papules became more flat and some began to desquamate. After the use hypodermically 0/ 1J gr. more^ the healing of the papules was complete^ and only small spots of a pale brown-red color remained. The disappearance of tlie glandular swelling had not taken place in the same proportion. Case 43.—Augusta Schn., thirty-eight years old, received into the Charite June 27th, 1866. Patient says her present disease was discovered only some six weeks ago, for which she had taken twelve sublimate pills and two bottles of medicine, the ingredients of which she was ignorant. Status prxsens: On the right labium maj. there was an ulcer of the size of a Mexican dollar, with an indurated base, covered with a fatty pus-like secretion. On the left labium min. there was an ulceration of less extension but of the same character. Pale brown scabs were visible on the right nostril. The skin of the whole body, especially on the back, chest and abdomen, tvas thickly covered toith a maculous exanthem, irregularly scattered about. Some loere topped with small scales, others were metamorphosed into diminutive papules. On both tonsils and on the seba- ceous glands at the root of the tongue, gray-white condylomatous ero- sions could be seen. The lymphatic glands were much swollen in the inguinal region, but only moderately in the submaxillary. The patient was treated at her own request with the '■'■ sarsaparilla sweat cure.''^ During the same, the maculae became more reddened, although some of the spots got paler and still others lead-colored. To our surprise, a lenticular papulous exanthem developed itself on the back and upper arm. After four weeks of the above treatment we suspended the same on account of increasing weakness and a tendency to vomiting. After a pause of eight days we observed an important increase of the papulous syphi- loid; besides, we detected that the ulcerations at the labia majora were not much softer, and therefore we determined to try the hypodermic medication. On account of the extreme debility of the patient, we injected only ■jJ^ gr. doses of sublimate, and soon increased to ^ gr., and then \ gr. After using but 1 gr. the ulcers were cicatrized over and their hardness very much diminished. The papules, which were already considerably reduced when | gr. had been used, were entirely gone ivhen 1 gr. had been administered, without leaving the