Thoughts on uræmia / by Gunning S. Bedford.

  • Bedford, Gunning S., 1806-1870.
Date:
[©1853?]
Catalogue details

Licence: Public Domain Mark

Credit: Thoughts on uræmia / by Gunning S. Bedford. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    toms—and what is still more significant is, that the ner- vous disturbance will yield in proportion to the effects of diuretic and sudorific remedies. There is no error as to the fact—its truth is readily susceptible of demonstration. 2d. A change in the Kidney, either structural or dynamic. Every structural change in the kidney may result in albu- minuria, but we do not yet comprehend in what essentially these various changes consist. For example, though it may be true that the presence of albumen in Bright's dis- ease, in scarlatina, &c., maybe due to a desquammation of Bellini's tubes, yet this cannot be said of many other dis- eases of the kidney, in which albuminuria exists, but in which no desquammation takes place. Several interesting experiments have been made to prove that the urinary se- cretion is not absolutely dependent upon the nervous sys- tem by Segalas, (1) and some of a more decisive charac- ter by Dr. Brown—Sequard; (2) whilst, on the other hand, it has been satisfactorily shown that the nervous system may, under certain circumstances, exercise a marked in- fluence over this secretion, as is demonstrated by the re- searches of Brachet, J. Muller,(3) and Marchand. The latter has pointed out a very important fact connected with this subject: he produced in a dog not only all the symptoms of uraemia, after placing a ligature on the renal nerves, but also discovered urea in the blood, and in the matter vomited by the dog. Kramer states that he has detected albumen in the urine of animals, after dividing the sympathetic nerve in the neck. This, however, seems to need confirmation, as the same result has not followed the experiments of others. Dr. Sequard, after repeated trials, has failed in establishing the fact mentioned by (1.) Bulletin des Seances de I'Acad. de Med. de Paris. (Seances des 27 Avut et 23 Septembre, 1844. (2.) Experimental researches applied to Physiol, and Pathol., Philad., 1852, '53, p. 13. (3) Manuel de Physiol, trad, frangaise de Jourdan. Edite par E. Littre, Paris, 1851; t. i., p. 391.