A report of microscopical & physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham.

  • Lewis, T. R. (Timothy Richards), 1841-1886.
Date:
1872
Catalogue details

Licence: Public Domain Mark

Credit: A report of microscopical & physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    Wo other special change. A post-mortem examination was made at 4 p. m. of the Post-mortem examination. Sa“e llay> atld We foUal1 tllat tlle peritoneal cavity contained reddish serous fluid. The peritoneum was not injected, and there were no signs of inflammation of the membrane. The sto- mach was empty, containing only about an ounce of glairy fluid, its mucous coat healthy. The duodenum was deeply congested and contained thick yellowish mucus. The congested surface, when wiped, resembled the hairs „ . . .. x of a hair pencil when flattened out. tmes, -with fluid resembling in the leninum the fluid was more that found in cholera. , . _ - _ watery and closely resembled that found in the intestines in cholera cases. In the lower part of the ileum there was less congestion of the mucous membrane, the contents here were foecal and not fluid, and towards the ileo-coecal valve the surface was quite pale. The large intes- tine was pink and contained pinkish mucus. There was a yellow patch at the edge of one of the lobes of the liver in which the minute vessels of the part presented a prominent tortuous appearance, evi- dently due to small local congestions. The spleen was large and showed numerous soft milky nodules on section. The kidneys were normal, not congested. The lungs healthy, collapsed and scarcely crepitant; the right cavities of the heart were full, the left empty. Experiment XLVI.—A little ordinary foecal matter was „ . . . , . . , diluted with about twice its weight of Materials used: a strained „ ° , solution of ordinary foecal water, allowed to stand tor twenty matter, 24 hours old. ’ . , . hours, and afterwards twice strained through three layers of muslin. The solution was then injected into the left femoral vein of a young dog whilst under the influence of chloroform. During the operation, the res- piratory movements suddenly ceased, but were re-established after artificial respiration had been persevered in for nearly ten minutes. The animal seemed to be quite comfortable during the Death in 29 hours after but night lie became sluggish, passing pinkish stools. passed reddish, liquid stools, and died on the following day, twenty-nine hours after the operation. The body was examined an hour and a half after death. , , There were no sians of peritonitis. Prune:juice like exudation in qqie stomach was empty, the duodenum intestines, and pneumonic i-no oiwiuavu »»_ patches in the lungs. contained yellowish, bile-stamed, fluid,