Report of the Committee of Management and Medical Director : 1946 / Papworth Village Settlement.

  • Papworth Village Settlement (Cambridge, England)
Date:
1946
Catalogue details

Licence: Public Domain Mark

Credit: Report of the Committee of Management and Medical Director : 1946 / Papworth Village Settlement. Source: Wellcome Collection.

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    4. Publications E. M. Brieger : Journal of Pathology, 1944 E. M. Brieger and Honor B. Fell : journal of Hygiene, 1945. 44. No. 3. E. M. Brieger and Honor B. Fell : journal of Hygiene, 1946 44. No. 4. E. M. Brieger and C. F. Robinow : journal of Hygiene, 1947 (now in the press). Acknowledgements. I wish to express my gratitude to Dr. Honor B. Fell, Director of Strangeways Research Laboratory, Cambridge, and Professor H. R. Dean, Department of Pathology, Cambridge, for their hospitality in putting at my disposal again facilities for the carrying-out of part of my research work at a time when the Papworth facilities are still inadequate, pending the execution of plans for the permanent accom¬ modation of the Research Department. THE SIMS WOODHEAD MEMORIAL LABORATORY D. Barron Cruickshank, LR.C.P. & S. (Edin)., L.D.S. (Edin.), D.P.H. (Camb.) Technical Asst. : F. Boot, A.I.M.LT. We have now been in occupation of the expanded Laboratory for approximately one year, and are finding the extra accommoda¬ tion of tremendous help. A brief account of some of our activities is given below. BACTERIOLOGY We are now using fluorescence microscopy as an aid to the detection of tubercle bacilli in sputum. This method, used by an increasing number of sanatoria, has recently been im¬ proved to such an extent that it has become a serviceable addition to existing methods. While its specificity equals that of the Ziehl- Neelsen method, the latter is so firmly established that its replacement in toto by the fluorescence method is not likely to happen before the passing of another decade. We use the method as an intermediary between Ziehl-Neelsen direct smear and cultures, and regard it as equivalent to a concentration method. Approximately 17 per cent of Ziehl-Neelsen negatives become positive by the fluorescence method. At present all results are checked by culture. We are also investigating its use in relation to slide culture technique; recognition of seven- day colonies is considerably facilitated by the use of fluorescence stains, and some photo¬ graphs of the effect are shown in this report. A communication Towards Fluorescence Micro¬ scopy, recording our experiences to date appeared in the May issue of Tubercle. Careful records of all routine sputum investi- Photographs of Colonies of M. tuberculosis from Sputum ; Fluorescence Stain. (7-Day Slide-Culture Technique) Original Specimen Ziehl-Neelsen +ve Original Specimen Ziehl-Neelsen —ve Direct Smear Direct Smear Standard magnification : 16 mm. objectiv^e ; X 10 ocular. [Reproduced by permission of “ Tubercle. |20]