Development of the early embryo

3D rendered flourescent image of a very early mouse embryo at around 5.5 days post fertilisation. The embryo has been labelled with two flourescent markers, one highlights the cell nuclei (Dapi) and shows the cells in blue and the other highlights the gap juntions (ZO-1) and highlights the region between the cells, indicating the orientaion and movement of these cells (red). A multi-cellular rosette is shown at the base of the embryo highlighted in different colours. It is these cellular formations that are thought to goven the orientation of growth and cell migration in the developing embryo. The whole embryo was imaged to get a stack of images that were then 3D rendered to get a surface view.