Report on the chemical pathology of the malignant cholera : containing analyses of the blood, dejections, &c. of patients labouring under that disease in Newcastle and London, &c. &c. &c. / by W.B. O'Shaughnessy.

  • O'Shaughnessy, William Brooke, 1809-1889.
Date:
1832
Catalogue details

Licence: Public Domain Mark

Credit: Report on the chemical pathology of the malignant cholera : containing analyses of the blood, dejections, &c. of patients labouring under that disease in Newcastle and London, &c. &c. &c. / by W.B. O'Shaughnessy. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    ) APPENDIX No. IV. MODE OF ANALYSIS OF CRASSAMENTUM. Whenever the separation of the blood into serum and crassa- mentum has been complete, and where the analysis of the former has been performed, the constituent parts of the latter can be as- certained with great precision by M. Lecanu’s method ; viz.— “ Divide 1000 parts of the clot into two parts—dry one, and estimate the loss—wash the other to ascertain the quantity of fibrine.* As the water given off from the first, exists therein in the state of serum, by subtracting the due proportion of solid matter (which the previous analysis of the serum has shown to be contained in 1000 parts thereof) in the interposed serum, from the( weight of the dried clot, the difference affords exactly the weight of the fibrine and colouring matter together. Subtracting again from this the weight of fibrine, determined by another experiment, the amount of the colouring matter is accurately obtained. Inci- neration, finally, of a given weight of the crassamentum, gives the quantity of saline matter.”—Journal de Pkarmacie, Sept. 1831. This was the process followed in the case of Dewar. See Appendix, No. II. par. 3. * The manipulation I recommend in this part of the process increases considerably in the accuracy of its results. T 2