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Subcellular fractionation : liver lysosomes and iron overload.

  • Peters, Thies.
  • Videos
  • Online

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Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
You can use this work for any purpose, as long as it is not primarily intended for or directed to commercial advantage or monetary compensation. You should also provide attribution to the original work, source and licence.
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Credit: Subcellular fractionation : liver lysosomes and iron overload. Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

About this work


Dr T J Peters lectures on the cell in health and disease, in particular the part of a cell's structure called the lysosome.


London : University of London Audio-Visual Centre, 1975.

Physical description

1 encoded moving image (26.22 min.) : sound, black and white.




Copyright note

University of London

Terms of use

Creative Commons Attribution-Non-Commercial 2.0 UK: England & Wales

Language note

In English

Creator/production credits

Presented by Dr T J Peters, Royal Postgraduate Medical School. Produced by David R Clark. Made for British Postgraduate Federation. Made by University of London Audio-Visual Centre.


This video is one of around 310 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and 1980s, thus constituting a contemporary medical-historical archive of great interest. The lectures mostly take place in a small and intimate studio setting and are often face-to-face. The lecturers use a wide variety of resources to illustrate their points, including film clips, slides, graphs, animated diagrams, charts and tables as well as 3-dimensional models and display boards with movable pieces. Some of the lecturers are telegenic while some are clearly less comfortable about being recorded; all are experts in their field and show great enthusiasm to share both the latest research and the historical context of their specialist areas.


Segment 1 Peters introduces the lecture. He shows electron micrographs and refers to diagrams and describes the appearance and function of a liver cell, a hepatocyte. Time start: 00:00:00:00 Time end: 00:06:01:00 Length: 00:06:01:00
Segment 2 A short film of a zonal rotor at work is shown. Peters explains in detail how it works. Time start: 00:06:01:00 Time end: 00:10:02:00 Length: 00:04:01:00
Segment 3 The short film of the zonal rotor continues to play. Time start: 00:10:02:00 Time end: 00:15:10:00 Length: 00:05:08:00
Segment 4 Peters describes the technique of microanalytical subcellular fractionation and talks about how it is applicable to several different areas of clinical medicine including the study of cardiac and intestinal tissues. Time start: 00:15:10:00 Time end: 00:21:11:00 Length: 00:06:01:00
Segment 5 Peters concludes with a discussion on how accumulated iron damages the lysosome and he assesses the evidence for and against this. Time start: 00:21:11:00 Time end: 00:06:01:00 Length: 00:06:11:13


  • English

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