Contribution to the study of non-cancerous tumours of the breast / by Charles Monod ; translated from the Archives gén. de médecine, January, 1875, by Charles Cullingworth ; to which is appended an account of an ovarian cyst in an infant newly born, by Charles J. Cullingworth.

  • Monod, Charles Edmond, 1843-1921.
Date:
1875
Catalogue details

Licence: Public Domain Mark

Credit: Contribution to the study of non-cancerous tumours of the breast / by Charles Monod ; translated from the Archives gén. de médecine, January, 1875, by Charles Cullingworth ; to which is appended an account of an ovarian cyst in an infant newly born, by Charles J. Cullingworth. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    projection, in form like a mushroom, which seems to be developed at the expense of one of their walls. This projection itself presents a pinked or furrowed {dechiqriede) surface ; it is subdivided into a great number of lobes, and smaller and smaller lobules, which give it a cauliflower aspect. The tissue of which it is composed, appears on sec- tion of the same nature as the rest of the tumour. Fre- quently, however, it is of softer consistence, and may even, according to the variety to which it belongs, be in process of softening. We shall see presently that this papillary appearance, which only reveals itself to the unaided eye when these vegetations have acquired a large size, is found under the microscope throughout the whole of the tumour, in different stages of development, from the simple upraising of the cyst-wall to the completely formed papilla. It is fully proved at this day that these hollow spaces, whose existence had not been overlooked by those occupied with the study of breast-tumours, are no other than the gland-cavities of the breast, abnormally developed and altered in form by the pathological tissue which has arisen in the gland. They have been described by M. Ranvier, under the name of kystes lacunaires, to distinguish them from true cysts, such as may be met with in tumours of the breast. All these cavities present a perfectly smooth surface, which recalls in every particular the appearance of an epithelial surface. It is easy, indeed, to show that they are really covered by epithelium. For this purpose it is sufficient, if the tumour has been recently removed, to let fall into the cavity of one of these cysts a solution of nitrate of silver 3 parts to the 1000 ; when permeation has occurred, a thin fragment of the cyst-wall is placed under the microscope, the section being parallel to the surface. An epithelial layer is at once recognised, in all respects similar to that which the wall of a normal gland duct would furnish under similar circumstances. This epithelium is found also on examination of thin sections under the microscope, made after hardening. These are the results furnished by this