Some clinical aspects of pernicious anaemia / by Herbert French.

  • French, Herbert Stanley, 1875-1951.
Date:
1909
Catalogue details

Licence: In copyright

Credit: Some clinical aspects of pernicious anaemia / by Herbert French. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    16/36 (page 216)
    Date. Eecl corpuscles per cub. inin. Red corpuscles per cent, of normal. Ilajinoglobin per cent, of normal. Colour index. 1893. May 24 800,000 16 30 1 -875 June .5 1.250,000 25 35 1 -400 ,, 20 2,100,000 42 50 1 -190 July 7 1,850,000 37 45 1 -216 21 2,750,000 55 60 1 -091 1894. January 15 500,000 10 18 1 -800 „ 28 1,150,000 23 February 6 900,000 18 20 1-111 March 7 ... 1,000,000 20 20 1 -000 » 22 900,000 18 18 1 -000 April 10 1,250,000 25 20 0-800 May 4 1,600,000 32 15 0-469 ,, 29 2,000,000 ‘ 40 30 0-750 June 8 1,850,000 37 19 0-512 Note.—There was no leucocytosis and films were typical of pernicious anaemia. Samuel D., aged 45, was admitted under the care of Dr. Hale White on December 23rd, 1893, and died on February 9th, 1894. He gave a history of having been dangerously ill six years pre- viously, with symptoms which were diagnosed as “ cholera,” though he had never been abroad. He recovered after some while, and enjoyed fair health on and off for five years. He then began to get progressively weaker, to lose his appetite, to suffer from very troublesome diarrhoea, and from breathlessness on ordinary exertion. He had been continuously under medical treatment from August, 1893. His height was 5 feet 5 inches, and his weight 8 st. without clothes. His skin had the primrose-yellow colour of pernicious ansemia. There were hajmic bruits in the mitral, aortic, and pulmonary areas, and in the neck. Neither liver nor spleen could be felt. The urine was dark, and contained both indican and uribilin, but neither albumen, blood, nor sugar. The optic discs and retina3 were at first natural, but later they developed haemorrhages. Much diarrhoea interfered with arsenical treatment. There was a very slight improvement for a time, then a relapse, and the patient