Organic acidurias : proceedings of the ninth symposium of the Society for the Study of Inborn Errors of Metabolism / edited by J. Stern and C. Toothill.

  • Society for the Study of Inborn Errors of Metabolism.
Date:
1972
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Organic acidurias : proceedings of the ninth symposium of the Society for the Study of Inborn Errors of Metabolism / edited by J. Stern and C. Toothill. Source: Wellcome Collection.

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    178 ORGANIC ACIDURIAS Fig. 2. Solvent 1 : Isopropanol-n-butanol-t-butanol-ammonia (0-88) water (40:20:20:10:20) 22 minutes. Solvent 2 ■. Benzene-acetic acid-water (70:29:1) 6 minutes. Normal subject: m-hydroxyhippuric and m-hydroxyhydacrylic acids. Cystic fibrosis: p-hydroxyphenylacetic acid (dominant). Phenylketonuria; o-hydroxyphenylacetic acid. Tyrosinosis: p-hydroxyphenyllactic acid with lesser amounts of /7-hydroxymandelic and p-hydroxyphenylacetic acids. and lignins; and also aliphatic compounds which can be converted into aromatic acids. Orange juice (Kefford & Chandler, 1970) and blackcur¬ rant juice (Morton, 1968) are particularly rich in these substances and are