Compensatory phenomena in the distribution of the blood during stimulation of the splanchnic nerve / by D.J. Edwards.

  • Edwards, Dayton James, 1882-
Date:
[1914]
Catalogue details

Licence: Public Domain Mark

Credit: Compensatory phenomena in the distribution of the blood during stimulation of the splanchnic nerve / by D.J. Edwards. Source: Wellcome Collection.

Provider: This material has been provided by the Augustus C. Long Health Sciences Library at Columbia University and Columbia University Libraries/Information Services, through the Medical Heritage Library. The original may be consulted at the the Augustus C. Long Health Sciences Library at Columbia University and Columbia University.

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    4j>jo. Reprinted from The American Journal of Physiology, Vo!. XXXV, No. 1 August, V.)U COMPENSATORY PHENOMENA IN THE DISTRIBU- TION OF THE BLOOD DURING STIMULATION OF THE SPLANCHNIC NERVE D. J. EDWARDS From the Department of Physiology, Columbia University, New York City ReoeivGcl for publication, May 18, 1914 A study of the transfer of the blood from the arterial to the venous side, during periods of vasoconstriction affecting the splanchnic area, requires the special consideration of two fac- tors; namely, the quantity of blood that flows through the portal circuit, and the quantity of blood that traverses other divisions of the circulatory system. The blood flow in the portal vein of the dog has been care- fully studied by Burton-Opit^,' measurements having been made upon the flow in the main trunk as well as in the tributaries. It has been shown that vasoconstriction in the abdominal vis- cera causes a marked diminution in the portal flow. The amount of decrease during a period of about 20 seconds of moderate stimulation of one splanchnic nerve was as much as one-fourth of the quantity normally flowing through this vein. In work upon the magnitude of the portal flow it is stated that a dog having an average body weight of 14.3 kgm. possesses a portal flow of 268.2 cc. per minute. If we assume that the total quantity of blood is one-thirteenth of the body Aveight, it is obvious that about one-fourth of the entire blood-supply nor- mally passes through the portal circuit. This would mean that about one-sixteenth of the blood of the animal, or approximately ' Burton-Opitz: Archiv fiir die gesammte Pliysiologie, cxxiii, p. 553, 1908; cxxiv, p. 495, 1908; oxxix, p. 189, 1909; cxxxv, p. 205, 1910; and Quarterly Journ. Physiol., 1911, iv, p. 113.