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Translocation - use of cosmid probe
- Wessex Reg. Genetics Centre
- Digital Images
- Online
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Attribution 4.0 International (CC BY 4.0)
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Credit: Translocation - use of cosmid probe. Wessex Reg. Genetics Centre. Attribution 4.0 International (CC BY 4.0)
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About this work
Description
Human chromosomes at metaphase, highlighted by
fluorescent probes that bind to specific base
sequences on the DNA. This cell has a
translocation between the X chromosome and a
chromosome 13 (X;13). The cosmid probe from the
XIST region (red) has not been disrupted by the Xq
break point. The use of such probes can help to
determine the break-points in the translocation.
(See also B0000313C)
Image by Dr John Crolla.