Prader Willi & Angelman's syndromes - probes
- Wessex Reg. Genetics Centre
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Human chromosome highlighted by fluorescent probes that bind to specific sequences of DNA. In this FISH (fluorescence in situ hybridisation) study a probe (red) from the Prader Willi and Angelman's syndromes critical region (PSASCR) and a chromosome 15 centromere specific probe (green) show that the 15q.11>q13 duplication does not include the PWASCR. Image by Dr John Crolla.