Prader Willi & Angelman's syndromes - probes
- Wessex Reg. Genetics Centre
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Description
Human chromosome highlighted by fluorescent probes
that bind to specific sequences of DNA. In this
FISH (fluorescence in situ hybridisation) study a
probe (red) from the Prader Willi and Angelman's
syndromes critical region (PSASCR) and a
chromosome 15 centromere specific probe (green)
show that the 15q.11>q13 duplication does not
include the PWASCR.
Image by Dr John Crolla.