Wounds of the pregnant uterus ; The effect of light on the staining of cells / by Leo Loeb.

  • Leo Loeb
Date:
1907
Catalogue details

Licence: In copyright

Credit: Wounds of the pregnant uterus ; The effect of light on the staining of cells / by Leo Loeb. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    2/4 (page 2)
    decidual tissue begins to take place normally, other stimuli are also able to call forth the production of decidual nodules. At the pres- ent stage of the investigation I do not, however, wish to deny pos- itively that a brief contact of the ovum with a wound of the uterus or with the inverted mucous membrane of the uterus is necessary for the production of decidual nodules. Between the third and fourth week after impregnation such nodules become necrotic. They resemble small tumors which originate under chemical stim- ulation, and are of a transitory character because the stimulus is transitory. They might be called benign deciduomata and be classed among that variety of new growths which I designated as transitory tumors and of which the corpus luteum might serve as a prototype. Among the animals experimented upon in the first three days of pregnancy, only once a deciduoma was found. These e.xperiments may also be of interest in so far as they seem to show that under ordinary conditions it is not possible to produce an abdominal pregnancy in the guinea pig by various injuries of the uterus ; although it may be assumed that under the conditions of the methods of experimentation adopted by me, the ovum had, in many cases, easy access to the abdominal cavity. In no instance did the peritoneal cavity show any change in the course of these experiments. We may, therefore, assume that the entrance of the ovum into the abdominal cavity is usually not sufficient to pro- duce an abdominal pregnancy. 65 (208) The elfect of light on the staining of cells. By LEO LOEB. Sj'vom the Laboratory of Experimental Pathology, University of Pennsylvania. ] Former studies of the structural changes in blood cells, especially of the behavior of cell granules under the influence of different external conditions, made it desirable to investigate the behavior of cells in different staining solutions, especially in solu- tions of vital stains. In the course of various investigations, it was found that solutions not only of eosin but also of other stains, as neutral red, affect the cells very differently in light and in dark. That eosin and other fluorescent substances are much more poison-