Amyloid fibrils, AFM

  • Dr. Wei-Feng Xue
  • Digital Images
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Amyloid fibrils, AFM. Dr. Wei-Feng Xue. Attribution 4.0 International (CC BY 4.0). Source: Wellcome Collection.

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False-colour, atomic force micrograph (AFM) showing the topography (surface contours) of beta2- microglobulin (b2m) fibrils (yellow) on a mica surface (ultraflat surface upon which the fibrils are imaged; red background). Fibrillar amyloid protein aggregates can be found in deposits or plaques associated with Alzheimer’s disease, Creutzfeldt-Jakob disease (CJD) and diabetes. The fibrils were formed in vitro. Image is 10 x 10 micrometres.

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