Pathological and clinical observations respecting morbid conditions of the stomach / by C. Handfield Jones.

  • Jones, C. Handfield (Charles Handfield), 1819-1890.
Date:
1855
Catalogue details

Licence: Public Domain Mark

Credit: Pathological and clinical observations respecting morbid conditions of the stomach / by C. Handfield Jones. Source: Wellcome Collection.

Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.

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    placed acid may be very irritating, certainly more so than a bland, mucous fluid. A very little clinical experience must convince any one of this. Simple enlargement of the gastric solitary glands has been seen and mentioned by Andral, but he was unac- quainted with the true nature of these bodies, and supposed the prominent spots to be formed by dis- tension of a follicle. He says that it is rare to find them in the stomach, but quotes from M. Billard the case of a child ten months old, in which the mucous surface of the stomach was dotted over, in all its extent, with a prodigious number of white granulations of the size of a millet seed. Similar ones existed in all the intestine. There can be little doubt that these granulations were enlarged solitary gland masses.* * The following interesting case has come under my notice while these sheets are passing through the press:—A robust, temperate man, set. 49, died quite suddenly about a quarter of an hour after a light supper. He had been under medical treatment for some weeks, on account of some symp- toms indicative of indigestion. These were chiefly eructation of frothy mucus and flatus generally in the morning, occasionally amounting to vomiting. The organs were found all very tolerably healthy, with the exception of the kidneys, which were granular, but not wasted materially. The stomach was much injected throughout, and contained much acid chyme and debris of food. The mucous membrane, all over its surface, presented numerous depressed spots, about the size of a split pea, resembling very much superficial ulcers; these were of oval, linear, or irregular shape, with rounded, not thickened edges, and smooth grayish bases; there was scarcely more vascular injection around them than in other parts. In the splenic and mid regions the tubes were healthy: in the pyloric they were a good deal obscured by diffused nuclear formation, and there were large nuclear masses in the substance of the mucous membrane. In the depressed (ulcerated) spots the tubes were more or less completely wasted, and the tissue was pervaded by diffused nuclear formation, with a circumscribed deposit here and there. The pancreas was in an advanced stage of fatty degeneration. In this case, the undue enlargement of the solitary glands caused, beyond doubt, wasting of the normal tubular structure in their vicinity. In this way depressions were formed, which may more properly be termed local atrophies than ulcerations. Had life been prolonged, the