Specification of Joseph Lawson Petingale : digestive mixtures.

  • Petingale, Joseph Lawson.
Date:
1876
Catalogue details

Licence: Public Domain Mark

Credit: Specification of Joseph Lawson Petingale : digestive mixtures. Source: Wellcome Collection.

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    Feting ale's Improvements in Digestive Miodures. be filed in the Great Seal Patent Office within six calendar months next and immediately after the date of the1 said Letters Patent. NOW KNOW YE, that I, the said Joseph Lawson Petingale, do hereby declare the nature of my said Invention,, and in what manner the same is to be performed, to be particularly described and ascertained in and 5 by the following statement:— Por this purpose I take of pepsine, pancreatine, and diastase, a greater or lesser proportion, according to the natere of the case. Eor instance, if the digestion of starchy matters is less active than the digestion of nitrogenous or fatty matters I use a larger proportion of diastase. 10 When the digestive power is desired to be increased in the stomach I relatively increase the pepsine beyond the proportion of the other two digestive principles, and when it is desirable to assist the digestion in the bowels the pancreatine becomes the more important constituent in the mixture, and must be increased in its proportion.* But' in all 15 instances I prefer to have an admixture of at least two of these principles, having found by experience that eaclh of these materially increases the digestive power of the other. Por the same reason I prefer for general purposes to have a certain amount of each of the digestive principles, and that these may exhibit a higher digestive power upon 20 food I furnish, together with the digestive compound, a dilute solution of hydrochloric and lactic acids, kept separate in a suitable vessel, and not mixed with the digestive principles until the latter are to be taken, or as I much prefer it to be taken after further dilution at from ten minutes to half an hour after the digestive compound has been 25 swallowed. Por generally unfeebled digestions I find a very useful proportional composition of the digestive compound to be as follows :—16 parts of pepsine, 12 parts of pancreatine, and one part of diastase, and this may be advantageously diluted with 80 parts of good sugar of milk. 30 The dilute hydrochloric or lactic acids furnished with the digestive compound as above should be again lowered in strength until the acidity present is equal to about one per cent, of concentrated hydrochloric acid. But I have found that when the acid solution contains greater acidity than would be represented by four per cent, of hydrochloric 35 acid the processes of digestion are arrested instead of stimulated, and if a lesser proportion is taken than one per cent, of acid it will require a