Note on the morbid anatomy of hypertrophic cirrhosis of the liver / by Robert Saundby.

Date:
1879
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Licence: Public Domain Mark

Credit: Note on the morbid anatomy of hypertrophic cirrhosis of the liver / by Robert Saundby. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    Reprinted from the Transactions of the Pathological Society of London for 1879.] Note on the morbid anatomy of hypertrophic cirrhosis of the liver. By Egbert Saundbt, M.D. Edin., M.E.C.P. Lond. For a long time the Erench pathologists have been aware that there are cases of hepatic cirrhosis which do not conform to the dictum of Bichat, “ Get etat ne se complique jamais du volume extraordinaire du foie.” In 1859 MM. Charcot and Luys presented a memoir to the Societe de Biologic, in which they maintained that the new growth in hypertrophic cirrhosis penetrates the lobules, is therefore intralobular, while in ordinary cirrhosis it surrounds the lobules and is perilobular. In 1871 M. Ollivier contributed a series of papers to the Union Medicale, in which he sought to estab- lish a separate clinical identity for these cases. In 1874 M. Hayem published a paper in the Archives de Physiologic, which contained an account of two cases of hypertrophic cirrhosis with microscopical descriptions, showing that the growth invaded the lobules, and, according to this observer, followed the course of the capillary blood-vessels. A few months later M. Cornil drew attention, in the pages of the same journal, to the numerous biliary canaliculi present in the dilated portal canals, fissures, and spaces of cirrhotic livers, especially of the hypertrophic form; an appearance which M. Cornil had described in 1871 in a case of acute yellow atrophy, which had run a somewhat protracted course. In 1875, M. Hanot wrote his inaugural thesis upon a form of hypertrophic cirrhosis accompanied by jaundice, for which he sought to establish a definite clinical and pathological position. During life the disease may be recognised, according to M. Hanot, by the history of early and persistent jaundice, the even enlargement of the liver, and the absence of ascites; anatomically, the liver is enlarged, its surface is