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- Dr Steve Wilson
- Digital Images
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Two zebrafish embryos at 3-4 days of development. The one on the bottom is the wild-type showing normal eye development. The one above has been injected with 'Sonic hedgehog' (Shh) RNA, a molecule which, when overexpressed, disrupts normal signalling in the developing forebrain. This results in greatly reduced eye development. (See also B0001092C)