The Wellcome Chemical Research Laboratories, London.

  • Power, Frederick B. (Frederick Belding), 1853-1927.
Date:
1914
Catalogue details

Licence: Attribution 4.0 International (CC BY 4.0)

Credit: The Wellcome Chemical Research Laboratories, London. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    exceptional interest, inasmuch as it has been found to consist, to a large extent, of the glyceryl esters of optically- Eictive acids of an entirely new type. These acids arc represented by the general formula CnH2„40.j, and have si, cyclic structure. The acid present in the largest pro- iportion possesses the formula Ci3H;;.Oj (m.p. 68°), and lhas been designated chaulwoogric acid, whilst a lower Ihomologue, C^H^O., (m.p. 6o°), has been termed Ihydnocarpic acid, on account of having first been isolated ifrom a Hydnocarpus oil. Both of these acids are beauti- fully crystalline substances, from which a number of (derivatives have been prepared, and their constitution lhas also been definitely established (Journ. Chem. Soc., -1904, 85, pp. 838-861 ; 1907. 91, PP- 557-578)- I The Seeds of Hydnocarpus Wightiana, Bltime AND OF Hydnocarpus anthelmintica, Pierre (“ Lukrabo ” Seeds) . Hydnocarpus Wightiana, Blume, is a tree indigenous to the Western Peninsula of India, whereas Hydnocar- Jnu anthelmintica, Pierre, is a native of Siam. The :seeds of the last-named species are exported to China under the name of “ Lukrabo,” and are there known as Ta-fung-tsze.” The fatty oils obtained from the seeds of these two plants have long been used in Western India and in China, respectively, for the same medicinal purposes for which chaulmoogra oil is employed. Both of these oils have been subjected to a complete investiga- tion, the results of which have shown them to resemble chaulmoogra oil very closely, both in their physical characters and their chemical composition. Like the true chaulmoogra oil, they consist to a large extent of the glyceryl esters of chaulmoogric and hydnocarpic acids (Journ. Chan. Soc., 1905, 87, pp. 884-896). The Seeds of Gynocardia odorata, A'. Hr. Cynocardia odorata, R. Br., is a native of Sikkim, Assam, and Chittagong in Bengal. The seeds of this plant were. It