Report on the bacteriological diagnosis and the antitoxic serum treatment of cases admitted to the hospitals of the Board during the years 1895 and 1896. / By G. Sims Woodhead.

  • Woodhead, G. Sims (German Sims), Sir, 1855-1921.
Date:
[1899?]
Catalogue details

Licence: Public Domain Mark

Credit: Report on the bacteriological diagnosis and the antitoxic serum treatment of cases admitted to the hospitals of the Board during the years 1895 and 1896. / By G. Sims Woodhead. Source: Wellcome Collection.

Provider: This material has been provided by London School of Hygiene & Tropical Medicine Library & Archives Service. The original may be consulted at London School of Hygiene & Tropical Medicine Library & Archives Service.

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    r INDEX PAGE Scarlet Fever {<f. Scarlatina). Scope of the Eeport . . .. . . 9 Serum, Antitoxic, about half is separated from Clot .. 116,117 ,, „ Behring's early Method of Testing . . . . 147 \, „ Burette for Filling in 119, 120, 121 Decanting of . . 120, 121, 122 ,, „ Distribution of . . . . 123 „ ,, Flask for Eeception of.. 119 Highly Potent, obtained 126, 130 ,, ,, Instructions for Use of. . 123 „ ,, Later Method of Testing 147 „ „ Percentage amount ob- tained from Blood . . 117 „ ,, Preparation of Tubes for 119 „ „ Preservation of, by Anti- septics .. . . 118 „ „ liapid Rise in Strength. . 128 ,, ,, Separation of, from Clot 116, 117, 118 „ ,, Slow Kise of Potency of 132 „ . Storage of .. 119,120,122 ,, „ Testing Potency of (see also Testing Antitoxic Serum) . . 147-148, 154-158 ,, ,, (cf. Antitoxin, Testing, Standardisation). Serum Toxin, Preliminary Treatment with 136 „ „ a modified Toxin .. . . 144 „ „ exerts little, if any, neutralis- ing effect on Antitoxin . . 148 „ „ Method of Preparation of Wood's 112 ,, „ Treatment of Horses with 124, 128, 130, 136 Serums supplied to the Hospitals . . 158, 160 „ sent out were Mixtures . . . . 159 Site of Membrane 37,38,39,63,64,162, 225-240 Smith's (Theobald) Method of Producing Toxin 103 Specimens, Preparation of . . . . . . 5 „ Transmission of . . . . 4,5 Spronck's Method of Producing Toxin . . 103 Stables, Description and Plan of the New 100-101 Staff Cases Examined . . . . . . 10 Stain, Loeffler's 6,8 „ Methylene Blue (see Loeffler's Stain). Staining by NicoUe's Method . . . . 6 Stall Accommodation . . . . 100, 101 Standardisation of Antitoxin (cf. Testing Antitoxic Serum). „ Toxin, Behring and Ehrlich's Method 109 „ ,, Behring's Nomen- clature . . . . 109 ,, ,, Determination of absolute Toxicity 150 ,, „ Difficulty of Pre- serving Standard 148 „ ,, Evidence of Neu- tralisation . . 149 „ ,, Factor of Age of Test Animal im- portant .. . . 109 „ „ Its Lethal Activity must be Neutra- lised . . . . 119 „ „ Necessity for . . ] 09 „ ,, Neutralising Values of Toxoids 151 ,, „ Newer Methods more Accurate . . 149 „ ,, Preservation of Test Toxins 152, 153 „ ,. Reaction between Toxin and Antitoxin 150 Continued. fAGB Standardisation of Toxin, Relative Values of Test Toxins . . 151 „ Roux's Method . . 109 „ „ Standard purely arbitrary . . 149 „ „ Test Toxins become Stable in time . . 153 „ ,, Two Neutralisa- tion Points . . 150 Staphylococci, Growth of . . . . . . 7 „ Presence of . . . . . . 21 Statistics, Cases in which Bacteriological Examination gave no Assistance 10,13 „ Cases in which Diphtheria Bacilli were found . . . . . 12 Copy of Record Sheet . . . . 10, U Number of Cases xidmitted . . 10, 12 ,, Preparation of . . . . . . 10, 11 Sterilisation of Burette for Serum. . .. 120 Stimulants, Cumulative Action of . . . . 130 Streptococci, Presence of . . . . . . 21 ,, Growth of . . . . . . 7 Swab, Description of . . . . . . 4 „ Examination of . . . . . . 5 „ Instructions for taking . . . . 4 Swelling, Local, in Injected Horses . . 113 Syntoxoids purely Theoretical Substances 152 ,, Definition of . . . . . . 151 Tempekatuee Reaction in Injected Horses 113 - Testing Antitoxic Serum, Apparatus used. . 154 ,, „ Average Annual Fall in Potency 159 „ „ Comparison of Results . . 157 ,, „ Description of Method . . 154 ,, „ Details of Injec- tion . , . . 154 ,, „ Details of Mixing 154 ,, Different Toxins used in .. 159 „ , „ Ehrlich's new Method . . 155 ,, „ Ehrlich's Report on . . . . 157 „ „ Experiments with Antitoxin sent toProf.Ehrlich 156 „ „ Instability of Antitoxin . . 159 ,, „ most Serums sent out were Mix- tures .. . . 159 „ „ Serums supplied to the Hospitals 158 „ „ Site of Injection 155 ,, ,, Sources of Fallacy 155 „ „ Test Animals ex- amined daily for four days. . 155 Test Toxins become Stable. . .. . . 153 „ Number of Lethal Doses in Test Dose 142 „ Preservation of , . . . 152 „ Relative Values of . . . . 151 „ (cf. Standardisation of Toxin). Tetanus Toxin less Stable than Diptheria Toxin 149 Toluol as Preserving Agent for Toxins . . 153 Tonsillar Abscess . . .. . . . . 43 Tonsillitis 55, 56, 57 Torula, Round . . . . . . . . 21 Toxin, Acid Bouillon unfavourable for Formation of . . . . , . 108 „ a Complex Substance ((/. Toxoids) 110