A note on some interesting results following the internal administration of arsenic in canker and other diseases of the foot in horses / by J.D.E. Holmes.

  • Holmes, John Dalrymple Edgar, 1867-
Date:
1913
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Licence: In copyright

Credit: A note on some interesting results following the internal administration of arsenic in canker and other diseases of the foot in horses / by J.D.E. Holmes. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    A Note on some Interesting Results following the Internal Administration of Arsenic in Canker and other Diseases of the Foot in Horses. WHILE carrying out experiments with arsenious oxide in the curative treatment of Surra in horses I had an opportunity of observing the effects of arsenic in certain other pathological condi- tions, especially that of canker of the foot. The value of arsenic in veterinary practice, as a general tonic, is well known and it is occasionally given to improve the coat and condition of horses. In all our experiments with Surra, which extended to three hundred or more ponies and horses, this tonic effect of arsenic was most marked. Animals in the last stage of emaciation rapidly regained their strength and condition. In these cases arsenic was administered in full sub-toxic doses, commencing at about one gramme and gradually increasing to about three grammes. Ten doses were given at an interval of one to two days between each dose. In some instances subcutaneous injections of atoxyl were given alternately with the arsenic by mouth. A full description* of this method of treatment, by which we have cured many cases of Surra in horses, has been previously published and need not be further described here. Canker of the Foot. Among a number of country-bred ponies, purchased for experi- mental work and which had been inoculated with Surra and were under treatment with arsenic, one was observed to be suffering from canker of the off-fore foot. The disease was of long standing, the foot being deformed, the heels contracted, and the sole covered with * Parasitology, Vol. Ill, pp. 73, 107. | Parasitology, Vol. Ill, No. 3, Oct. 1910.