Animals for research : principles of breeding and management / edited by W. Lane-Petter.

Date:
1963
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Animals for research : principles of breeding and management / edited by W. Lane-Petter. Source: Wellcome Collection.

    48/560 (page 26)
    26 G. PORTER and lactation in CBA inbred mice. In this instance production progressively declined with each successive generation, A feeding regime adequate for both rats and mice is at present generally accepted by the majority of laboratories. However, although experimental evidence has estabhshed strain differences in mice and rats, there is little evidence of a species difference. It is probably safe to say that until further evidence is available the mouse may be taken as the more sensitive indicator. The requirements of the two species have been reviewed by many workers including Morris (1944), McCoy (1949), Brown and Sturtevant (1949), Worden (1957) and Cuthbertson (1957), All these workers found results similar to those shown in Tables V-VIII (after Cuthbertson). Table V Water-soluble Vitamins Vitamin Rat Quantity per kg food Reference Mouse Quantity per kg food Reference Thiamine Riboflavine Pantothenate Vitamin Bia 1-25 mg 2-5 mg 5 0 mg 2-5 mg 10 mg 10 mg 15-20 iug 20-25 Mg Not required Brown and Sturtevant (1949) Brown and Sturtevant (1949) El Sadr et al. (1940) Coward (1952) Brown and Sturtevant (1949) Coward (1952) Cuthbertson and Thornton (1952) Emerson (1949) Coward (1952) Nicotinic acid None, imless diet Hundley (1947) (amide) deficient in tryptophan 10-100 mg Cuthbertson (1957) Pteroyl None, unless gut Glutamic acid synthesis prevented 0'6-2-0 mg Biotin Pyridoxine Inositol Choline None, unless gut synthesis prevented 100-400 Mg 1-2 mg 1-0 mg 1-5 mg 1-0 mg Not required 3 g 300 mg 1-2 g 10 g Asen jo (1948) Darke and White (1950) Cuthbertson (1957) Nielson and Elvehjem (1941) McCoy (1949) Brown and Sturtevant (1949) Sarma et al. (1946) Coward (1952) Coward (1952) Cunha et al. (1943) Engel (1942) Glynn et al. (1948) Conger and Elvehjem (1941) Engel (1942) 3 mg 1-5 mg 4-0-6'0 mg 4-0 mg 1-5 mg 3 mg as d- calcium pantothenate 5 Mg 10-20 Mg Morris (1947) Morris (1947) Fenton and Cowgül (1947) Coward (1952) Fenton et al. (1950) Coward (1952) Jaffé (1950) Bosshart et al. (1950) Probably not required, unless diet deficient in tryptophan 10 mg Essential Cuthbertson (1957) 1 mg Essential for lactation 80 Mg Not determined 1 mg 5 mg 10-100 mg Not determined Essential 10 g Not determined Nielson and Black (1944) Fenton and Cowgül (1947) Cuthbertson (1957) Fenton and Cowgill (1947) Cuthbertson (1957) Coward (1952) Morris (1947) Fenton and Cowgill (1947) Wooley (1941) Spitzer and Phillips (1946) Coward (1952) Mirone (1954) Cuthbertson (1957) Coward (1952)