The nervous and chemical regulators of metabolism : lectures / by D. Noël Paton.

  • Paton, Diarmid Noël, 1859-1928.
Date:
1913
Catalogue details

Licence: In copyright

Credit: The nervous and chemical regulators of metabolism : lectures / by D. Noël Paton. Source: Wellcome Collection.

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    With the large series of experimental investiga- tions upon the effects of removal of the central nervous system in larval amphibia, we need not concern ourselves further than we have already done. As already pointed out, the undoubted persistence of the influence of hereditary inertia and the possible blending of this with the influence of the nervous system at this stage makes the interpretation of results most difficult, and of little value in the solution of the question. To what extent does the nervous system dominate the metabolism ? One interesting set of observations by Diirken may be referred to. He shows that in young tadpoles there is a marked co-relation between the “ Anlage of the limbs and the central nervous system, and that removal of one of the limb-buds may be followed by failure in the development in certain definite parts of the nervous system—in peripheral nerves, spinal ganglia, motor cells of the spinal cord and even in the hind and fore brain. In some cases he finds that destruction of one limb-bud is followed by malformations of others, and that these are also associated with changes in the central nervous system. These results indicate a close co-relation- ship between the nervous system and the develop- ing tissues, and support the view that the former undoubtedly acts upon the latter and is reacted upon by it. It is unnecessary to discuss the large series of observations which have been carried out upon