Cellular pathology : as based upon physiological and pathological histology; twenty lectures delivered in the Pathological Institute of Berlin during the months of February, March, and April, 1858 / by Rudolf Virchow; translated from the second edition of the original by Frank Chance; with notes and numerous emendations, principally from ms. notes of the author.

  • Virchow, Rudolf, 1821-1902.
Date:
MDCCCLX. [1860]
Catalogue details

Licence: Public Domain Mark

Credit: Cellular pathology : as based upon physiological and pathological histology; twenty lectures delivered in the Pathological Institute of Berlin during the months of February, March, and April, 1858 / by Rudolf Virchow; translated from the second edition of the original by Frank Chance; with notes and numerous emendations, principally from ms. notes of the author. Source: Wellcome Collection.

Provider: This material has been provided by King’s College London. The original may be consulted at King’s College London.

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    completed, about wliicli new matter gradually gathered, and in due time produced a little membrane (the celebrated watch-glass fonn, fig. 4, d'). This description of the first development of cells out of free blastema, according to which the nucleus was regarded as preceding the formation of the cell, and former {cytoblast), is the one which is usually concisely designated by the name of the cell- theory (more accurately, theory of free cell-formation),—a theory of development which has now been almost entirely abandoned, and in support of the correctness of which not one single fact can with certainty be adduced. With respect to the nucleolus, all that we can for the present regard as certain, is, that where we have to deal until large and fully developed cells, we almost constantly see a nucleolus in them; but that, on the contrary, in the case of many young cells it is wanting. You will hereafter be made acquainted with a series of facts in the history of pathological and physiological de- velopment, which render it in a high degree probable that the nucleus plays an extremely important part within the cell—a part, I will here at once remark, less connected with the function and specific office of the cell, than with its maintenance and multiplication as a living part. The specific (in a narrower sense, animal) function is most dis- tinctly manifested in muscles, nerves, and gland-cells; the playing the part of a real cell- Fig. 4. From Sclileiden, ‘ Grundziige der wiss. Botanik,’ I, fig. ]. “ Contents of tlie embryo-sac of Vida faba soon after impregnation. In the clear fluid, consisting of gum and sugar, granules of protein-compounds are seen swimming about {a), among whieli a few larger ones are strikingly conspi- cuous. Around these latter the former are seen conglomerated into the form of a small dise {b, c). Around other discs a clear, sharply defined border may be distinguished, which gradually recedes farther and farther from the dise (the cytoblast), and, finally, can be distinctly recognised to be a young cell (</, <;).”