The fungus-disease in India : a report of observations / by T.R. Lewis and D.D. Cunningham.

  • Lewis, T. R. (Timothy Richards), 1841-1886.
Date:
1875
Catalogue details

Licence: Public Domain Mark

Credit: The fungus-disease in India : a report of observations / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    fat lobules were apparently in the normal state, or only altered to a trifling extent. Some of these altered lobules found in preparations of the dark variety of the disease have contained dark granules. The accompany- ing wood-cut of a dissection under a low power of a little group of this kind will more clearly convey our meaning. A little of the subcutaneous tissue from over the ankle joint of Specimen II (page 49) was removed and spread out under the dissecting microscope for the purpose of examining a minute dark speck in the midst of what seemed to be normal adipose tissue, and which seemed likely to prove to be the peculiar dark substance found in connection with the malady, enclosed in a capsule. This encysted little mass was found lying be- tween two somewhat hardened, otherwise normal, healthy en- cysted aggregations of fat, as delineated in the engraving (Fig. 7), in which the lining membrane surrounding the dark material is represented as torn open. This capsule was, how- ever, more dense than the cap- sules surrounding the ordinary SeS«rbtkt3s ^ e! fat masses, although it resem- bled them in general appearance. Microscopically i consisted of connective tissue, but with a smalle proportion of elastic fibres than those of the norm capsules. It was easily teased out. The material en closed by the capsule consisted of an aggregation smooth, black, ova-like particles, each of which w contained in a separate fibrous capsule similar in stru ture to the general investing capsule, so that the bodie were, although closely aggregated, quite distinct fro one another. The black matter could be readily presse out from the capsules, leaving the latter more or les empty. Whatever may be the nature of the agent whic determined the formation of this minute saccule of dar granules in the midst of saccules of fat cells, it Fig. 7.—Three encysted mass- es of altered adipose aiwd con- nective tissue. The centre one