Find thousands of books, manuscripts, visual materials and unpublished archives from our collections, many of them with free online access.

Charcot Leyden crystals from an endobronchial lesion

  • William R. Geddie
  • Digital Images
  • Online

Available online

view Charcot Leyden crystals from an endobronchial lesion

Licence

CC0 1.0 Universal
You can use this work for any purpose without restriction under copyright law.
Creative Commons Zero (CC0) terms and conditions https://creativecommons.org/publicdomain/zero/1.0
Credit: Charcot Leyden crystals from an endobronchial lesion. William R. Geddie. CC0 1.0 Universal

Selected images from this work


About this work

Description

Some types of asthma are characterized by chronic inflammation of the lungs. This can lead to formation of thick, gelatinous mucus, which can obstruct the bronchi of the lungs and mimic tumours. In order to investigate such blockages, samples can be obtained using a technique called Endobronchial Ultrasound - Transbronchial Needle Aspiration (EBUS-TBNA) and analyzed using a Papanicolaou stain to detect malignant and abnormal cells. The image shows a "cotton wool" like background of fibrin (a product of tissue damage) and clumps of necrotic (dead and dying) white blood cells called eosinophils. Pointed bipyramidal Charcot Leyden crystals can be seen, which are actually hexagonal when seen in cross section. Charcot Leyden crystals are formed when numerous eosinophils release their enzymes (lysophospholipases). The specimen in this case has been examined using differential interference contrast microscopy which utilizes a combination of prisms and polarisers to refract light, and which is perceived by the eye as a three dimensional effect. Horizontal image width 215 micrometres

Contributors



Permanent link