The surgical diseases of the genito-urinary organs including syphilis / by E.L. Keyes ; a revision of Van Buren and Keyes's text-book upon the same subjects.

  • Keyes, E. L. (Edward Lawrence), 1843-1924.
Date:
1889, ©1888
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Licence: Public Domain Mark

Credit: The surgical diseases of the genito-urinary organs including syphilis / by E.L. Keyes ; a revision of Van Buren and Keyes's text-book upon the same subjects. Source: Wellcome Collection.

Provider: This material has been provided by the Augustus C. Long Health Sciences Library at Columbia University and Columbia University Libraries/Information Services, through the Medical Heritage Library. The original may be consulted at the the Augustus C. Long Health Sciences Library at Columbia University and Columbia University.

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    pear upon cli.^contimiing the drug, or change of air. The exliibition of cod-liver oil, astringent preparations of iron, and other hygienic and tonic measures, are indicated. Purpura due to the iodides was noticed by Kicord. and written about by him as early as 1842. (4) A ju'cidiar bullous eruption due to the ingestion of the iodide of potassium has been noted by many observers who have written ex- haustively about it. Eicord first described it as a rui>ia. I have seen only two cases in which tliere were groups of bull;v scattered over the body, mainly upon the trunk and face, and a moderate number of separate single lesions. Most of the bulhi^ were umbilicated at first, and some of them readied a large size. The possibility of confound- ing it with varioloid has been pointed out. Its course, however, is different, and any attentive observer can not fail soon to refer it to its true source. Among the writers who have noted it are Bradbury, Virchow, Bumstead, Boinet, Pinger, Cazenave, Hutchinson, Taylor, Fournier, Duhring, Hyde, T. Fox, Finney, Duckworth, Farquharsen, Pellizzari, Van Ilarlingen, Morrow, Tilden, and others. Thin * has described it pathologically. Hyde \ intimates that all the iodic bul- lous eruptions may bo grouped into three sub-forms : 1. Simple bulla, seen in the old and cachectic. 2. A rarer polymorphic form—bulla3 mingled with papules, macules, and tubercles. 3. A quasi-bullous eruption, first described by T. Fox, and resembling variola—a rare form found on the face, backs of the arms, and forearms—a semi-solid umbilicated lesion which does not collapse on puncture, being filled with insi)issated grumous contents. These lesions shrivel or dry to a crust when the use of the iodide is suspended. 5. Anmmia with Nervous Prostration.—I have seen several cases in which patients long under treatment for severe nervous lesions due to syphilis, by continuing their treatment too long and at too high a dose, gradually became anaemic without losing flesh, restless, nervous, de- spondent, tremulous, unable to eat, and apparently too weak to do any work. I have seen two patients from this cause give up work and one of them pre^^are to die. One could not sign his name, so weak and unsteady was he, and yet both recovered in a few weeks after leav- ing off the iodide, going away from town, and resorting to general tonic measures : milk, phosphates, rest, and the like. 6. Albuminuria.—I have also seen more than once very mild albu- minuria with hyaline casts coincide with the use of very large doses of the iodide of potassium. Xo symptoms of ordinary albuminuria attended this state of affairs, and the albumen and casts promptly dis- appeared on leaving off the drug. This phenomenon is not at all com- mon in my experience. Most patients support the largest doses they can tolerate without showing any sign on the part of the kidneys. I * Medico-chir. Trans., vol. Ixii, 1879, p. 189. \ Journ. of Cutaneous and Venereal Diseases, December, 1886, p. 853.