The relation between natural and synthetical glycerylphosphoric acids. Pt. 2 / by Frank Tutin and A.C.O. Hann.

  • Tutin, Frank.
Date:
[1906]
Catalogue details

Licence: In copyright

Credit: The relation between natural and synthetical glycerylphosphoric acids. Pt. 2 / by Frank Tutin and A.C.O. Hann. Source: Wellcome Collection.

    7/14 (page 1753)
    removed as oxalate. An excess of barium hydroxide solution was added to the filtrate, and the liquid boiled until free from ammonia. After cooling, the excess of baryta was removed by means of carbon dioxide, and the filtered solution evaporated to a small bulk. The barium a-glycerylphosphate which separated was recrystallised from water, when it was obtained in glistening leaflets. This salt, like the barium salts of the other preparations of glycerylphosphoric acid, dissolves more sparingly in hot than in cold water. 0-4975 of air-dried salt, when heated at 1*25°, lost 0 0052 H„0. H20 = 1 -o. C3H706PBa,I Ft,0 requires H.,0 = 2 8 per cent. 0-4923, dried at 125°, gave 0*3722 BaS04. Ba = 44*5. C3Hij.06PBa requires Ba = 44*6 per cent. The solubilities of this and succeeding barium salts were determined by parallel experiments, conducted at the same time, in the following manner. A quantity of the pure salt was placed in a small stoppered bottle and mechanically shaken for eleven hours with about 15 c.c. of water. The temperature of the liquid was 1 7°. A weighed quantity of the filtered solution was then evaporated to dryness on a water-bath, and the residue weighed. 6*6122 of the solution gave on evaporation 0-2484 of residue, therefore oue part of the salt is contained in 26-6 parts of solution. /O' CH2* CH (OH) • CH2* O H Brucine a-Glycerylphosphate, O — P(-0H,C.rJH.v04N2.—The brucine N>H,C„H*04N, salt of a-glycerylphosphoric acid, as well as the brucine salts subse¬ quently described,was prepared by precipitating exactly a solution of the respective barium salt with a solution of brucine sulphate, the barium sulphate being removed by filtration. Brucine a-glycerylphosphate readily crystallises from water in rosettes of needles, which, after drying at 100°, melt at 157—158°. 0 3074 of air-dried salt, when dried at 100°, lost 0 0443 H20. H20= 14-4. In order to ascertain whether the amount of water of crystallisation was a constant quantity, the salt was Yecrystallised from a dilute solution, and again allowed to dry in the air. 0*3016, on drying at 100°, lost 0*0436 il20. Ho0 = 14*5. The air-dried and the dehydrated salts were then analysed : 0*2021 of air-dried salt gave 0*3860 C02 and 0*1270 IIgO. C = 52*l ; II = 7*0.