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The Mediterranean anaemias : thalassaemia.

Date
1973
  • Videos

About this work

Description

The thalassaemia disorders are the most common single gene conditions which produce a major worldwide problem. With the increasing immigrant population, they are often being seen in the United Kingdom. This programme describes the clinical and genetic features of these disorders and reviews recent studies regarding their molecular biology.

Publication/Creation

London : University of London Audio-Visual Centre, 1973.

Physical description

1 encoded moving image (29.06 min.) : sound, black and white.

Duration

00:29:06

Copyright note

University of London

Terms of use

Restricted

Language note

In English

Creator/production credits

Presented by Professor David Weatherall. Introduced by Dr Ian Gilliland. Produced by Kevin Sharp. Made by University of London Audio-Visual Centre. Made for British Postgraduate Medical Federation.

Notes

This video is one of around 310 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and early 1980s, thus constituting a contemporary medical-historical archive of great interest.

Contents

Segment 1 Gilliland introduces Weatherall. Weatherall shows a diagram of a haemoglobin molecule and explains its structure. Time start: 00:00:00:00 Time end: 00:05:10:00 Length: 00:05:10:00
Segment 2 Weatherall refers to a diagram illustrating the genetic control of amino acid chains in haemoglobin and a chart showing the classification of thalassaemias. Time start: 00:05:10:00 Time end: 00:09:33:00 Length: 00:04:23:00
Segment 3 A photograph is shown of a child with beta thalassaemia and Weatherall then describes what can be seen in photomicrographs of red blood cells and bone marrow from a child with beta thalassaemia. A photograph of a stillborn baby is shown. Time start: 00:09:33:00 Time end: 00:14:56:00 Length: 00:05:11:00
Segment 4 A diagram is used to explain the defective pathway in haemoglobin H disease. Weatherall refers to a diagram which illustrates genetic control of protein production. A further diagram is used to illustrate the outcomes of different defects in protein synthesis pathways. Time start: 00:14:56:00 Time end: 00:20:45:00 Length: 00:05:49:00
Segment 5 Diagrams of defective haemoglobin and globin chain syntheses are shown. Time start: 00:20:45:00 Time end: 00:24:38:13 Length: 00:03:53:13
Segment 6 Weatherall shows a diagram detailing mRNA to cDNA pathways, then concludes the lecture. Time start: 00:24:38:13 Time end: 00:29:06:19 Length: 00:04:28:06

Languages

  • English


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