Genetics in obstetrics and gynecology / Joe Leigh Simpson [and others].

Date:
[1982], ©1982
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Genetics in obstetrics and gynecology / Joe Leigh Simpson [and others]. Source: Wellcome Collection.

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    320 / INDEX Teratogens [continued] alcohol, 257 chemical, 248 drugs androgens, 253-254 anesthetic agents, 262 antianxiety agents, 258-259 anticoagulants, 261-262 anticonvulsants, 260-261 antihypertensives, 263 antimicrobial agents, 251-253 antinausea agents, 263 antineoplastic agents, 249-251 antipsychotics, 259-260 aspirin, 262-263 commonly abused, 257-258 diuretics, 263 estrogens, 254-255 hormones, 253-256 lithium, 260 LSD, 257-258 penicillamine, 264 vitamins, 263-264 environmental agents, 264-265 Teratomas, ovarian, genetics of, 153 Testes, rudimentary, 173 Testicular determinant, on Y chromosome, 156—158 Testicular feminization, 91, 147 complete description of, 168-169 genetics of, 168-169 neoplasms associated with, 169- 170 pathogenesis of, 170 incomplete genetics of, 170-171 Reifenstein syndrome and, 170— 171 Tetracycline, teratogenicity of, 251-252 Tetralogy of Fallot, 84 Tetraploidy definition of, 73-74 spontaneous abortion associated with, 125-126 Thalassemia syndromes, 35-37 alpha-, 36, 120 beta-, 36-37, 120 hemoglobin S-beta thalassemia, 38 pregnancy, effects of on, 38 prenatal diagnosis of, 106-107, 113- 114 reproduction, effects of on, 38 Thalidomide, teratogenicity of, 258 Thiourea agents, teratogenicity of, 256 Thrombasthenia, 41 Thrombocytopenia, 41 Thyroid gland diseases and pregnancy, 45 safety of hormones in pregnancy, 256 Toxoplasmosis, 239-243 clinical manifestations of, 241-242 in mother, 241 in neonate, 241-242 diagnosis of, 242 incidence of, 228, 240 pathophysiology of, 240-241 treatment and prevention of, 242— 243 Tracheoesophageal fistula, 87-88 associated defects, 88 recurrence risk of, 88 Translocation, general aspects, 19-20. See also Autosomal abnormalities nomenclature, 10, 12 prenatal diagnosis of, 104 radiation-induced, 222, 223 reciprocal, 11 spontaneous abortions and, 130-132 Transposition of great vessels, 86 Trimethadione, teratogenicity of, 261 Triploidy, 73-74 cytologic causes of, 73-74, 125 phenotype, 74 in spontaneous abortion, 125 Trisomies. See also Autosomal abnormalities; Nondisjunction; Sex chromosomal abnormalities clinical features of, 55 — 73 definition of, 17 mental retardation in, 96 and parental age, 54, 103, 129 radiation associated with, 223 recurrence risk of, 104 in spontaneous abortion, 124-125 Trisomy 8 genetic counseling in, 70 phenotype, 70 recurrence risk of, 70 Trisomy 9 genetic counseling in, 72-73 phenotype, 72 Trisomy 13, 64-67