The Friedmann treatment for tuberculosis : a report of the board appointed for its investigation / by John F. Anderson and Arthur M. Stimson.

  • Anderson, John F., 1871-1958
Date:
1914
Catalogue details

Licence: In copyright

Credit: The Friedmann treatment for tuberculosis : a report of the board appointed for its investigation / by John F. Anderson and Arthur M. Stimson. Source: Wellcome Collection.

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    No. 47. T. B.—Lupus of face—Tubercular glands of neck.—Lupus of one year’s duration, beginning as papules on left cheek and nose; slowly progres¬ sive. Had tubercular glands at angle of jaw three years ago, which broke , down, discharged pus, and healed; now has enlarged glands in the submental and submaxillary region. Lupus involves isolated areas on nose and cheek and upper lip. Pathological diagnosis made from material from septum. Treatment, March 22, 0.1 c. c. intramuscularly; marked febrile reaction, formed infiltration, which eventuated in abscess. Treatment, March 22, 1913, 0.1 c. c. intravenously; marked febrile reaction. Result : After about three months no decided change could be determined. Some tuberculous elevations had decreased in size, while others had increased. The submental glands broke down and still continue to discharge. The site of injection was occupied by a purplish scar, which broke down and discharged intermittently. Summary : Here is an instance where the simultaneous injection failed to prevent abscess formation. No significant curative effect took place. March 29, 1914. Seen at home. No significant improvement having fol¬ lowed the Friedmann treatment, the patient consulted a private physician, under whose care the condition improved greatly. Without apparent reason, three weeks ago it suddenly began to get worse again and is now more extensive than at the time of treatment. No. J/8. E. H., 17 years—Pulmonary tuberculosis, II.—Cough three years. Early hemorrhages; none since. Lost 10 pounds in two years before admis¬ sion. Fever at first only. Complains of weakness. Temperature now seldom reaches 99.5°. Gained weight recently. Tubercle bacilli in sputum. 'Pirquet positive. Infiltration left upper lobe. General condition fairly good. Treatment, March 22, 1913, 0.15 c. c. intramuscularly; local infiltration de* layed six weeks. Result : Early improvement in subjective symptoms, followed by their re¬ turn, and gradual improvement again. One month after the injection the physical signs indicated progress of the lesion. Three months after injection some improvement observable. Cough practically disappeared. Expectorates once or twice a day. Temperature subnormal. Weight stationary since treat¬ ment. Signs show less moisture; few rales except on coughing. Sanatorium conditions much of the time. Summary : Improvement could be readily accounted for by excellent sur¬ roundings. No. 49. F. E., 17 years—Pulmonary tuberculosis, II.—Four years’ duration. One early hemorrhage and one since. Improved to arrested condition two years ago. Since then slowly progressive. Does well while at rest; under sanatorium conditions; has fever on attempting to return to work. Temperature now normal to 99°; has gained only 2 pounds in two years. Tubercle bacilli found in sputum only after many examinations. Infiltration of both apices and left lung to the lower end of the scapula. Treatment, March 22, 1913, 0.2 c. c. intramuscularly; large lasting induration. Result: Three months after injection feels the same as before treatment; temperature, maximum 100°; usually subnormal; a very small hard nodule at the sight of injection. Physical examination shows no significant change in condition. March 16, 1914. Seen. Condition practically the same as last year. Ts in sanatorium. Has gained only 7 pounds in the past year, and most of that since coming to the sanatorium. Cough and expectoration slight. Sputum con¬ tains tubercle bacilli. Chest signs practically the same as before.