A companion to the British pharmacopoeia : comparing the strength of the various preparations with those of the London, Edinburgh, and Dublin, United States and other foreign pharmacopoeias, with practical hints on prescribing / by Peter Squire.

  • Squire Peter Wyatt, Sir, 1847-1919.
Date:
1866
Catalogue details

Licence: Public Domain Mark

Credit: A companion to the British pharmacopoeia : comparing the strength of the various preparations with those of the London, Edinburgh, and Dublin, United States and other foreign pharmacopoeias, with practical hints on prescribing / by Peter Squire. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

    118/324 (page 98)
    Solution of Persulphate of Iron, 8; Solution of Ammonia, 14 ; Citric Acid in crystals, 5 ; Distilled Water, 80: add the Iron to 40 of water; gradually add this to the Ammonia, stirring well for a few minutes ; collect the Hydrated Peroxide of Iron which precipitates, and wash it until the filtrate ceases to become turbid on the addition of Chloride of Barium. Dissolve the Citric Acid in the remainder of the water, and digest at a boiling heat on the Oxide of Iron. Make the liquid neutral by the addition of Solution of Ammonia, and evaporate to dryness in thin layers on flat porcelain or glass plates. Keep the salt in flakes in stoppered bottles. Soluble in water, 10 in 5 ; almost insoluble in Rectified Spirit. Ted.—Its solution in water, when acidulated with Hydrochloric Acid, gives a copious blue precipitate with the Ferrocyanide of Potassium—indi- cating Peroxide; but none with the Ferridcyanide—indicating absence of Protoxide. When incinerated with exposure to air, it leaves 26*5 per cent, of Peroxide of Iron. Medicinal Properties. As a blood restorer it is a very eflFectual salt, and it possesses scarcely any astringency : it may often be given when the stomach will not bear the more astringent preparations of iron. (Lond. Dub. Ferri Ammonio-Citras ; and U. S.; not in others.) Dose.—5 to 10 grs. In prescribing the above Salt to be taken during effervescence care must be taken to put tlio Salt of Iron into the Citric Acid Solut ion, and not into the Bicarbonate of Potash Solution, because if it be put into the latter, Carbonic Acid will be given off and the bottle burst. Tincture of Orange is the best flavouring agent, but prescribers arc in the habit of ordering this Salt ui Tincture of Orange Peel alone, in which it will not dissolve, therefore the division into doses is impracticable. The addition of only a small quantity of water will make the solution perfect. PERRI ET QUINI.^ CITRAS. CITRATE OF IRON AND QUININE. Citric Acid combined with Peroxide of Iron, Protoxide of Iron, and Quinia. Thin scales of a greenish golden-yellow colour, somewhat deliquescent, Brit. Ph. The process given, however, by the Brit. Ph. produces scales of a garnet colour. Solution of Persulphate of Iron, 3 oz.; Sulphate of Iron, 1 oz.; Distilled Water, q. s.; Solution of Soda, 36 oz.; Citric Acid, in crystals, 3^ oz.; Sulphate of Quinia, 380 grs.; Dilute Hydrochloric Acid, Solution of Chloride of Barium, and Solution of Ammonia, of each a sufficiency. Dissolve the Sulphate of Iron in 10 oz. of Water, and add to the solution of Persulphate of Iron, mix well, and pour into the solution of Soda, con- stantly stirring. Collect the precipitate on a calico filter, and wash it until the filtrate ceases to give a precipitate with Chloride of Barium. Dissolve the Citric Acid in 20 oz. of Water, add the waslied precipitate, digest on a water bath, repeatedly stirring until a solution is obtaiued. Dissolve the Sulphate of Quinia in 8 oz. of the Water acidulated with a little of the dilute