An inaugural treatise on veratrine : offered to the dean and faculty of the Medical College of the State of South-Carolina / by Charles Rabe.

  • Rabe, Charles.
Date:
1843
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Licence: Public Domain Mark

Credit: An inaugural treatise on veratrine : offered to the dean and faculty of the Medical College of the State of South-Carolina / by Charles Rabe. Source: Wellcome Collection.

Provider: This material has been provided by the National Library of Medicine (U.S.), through the Medical Heritage Library. The original may be consulted at the National Library of Medicine (U.S.)

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    tablish any fixed characteristic, whereby to detect its presence. Nitric acid, which colors Strychnine red, does not act similarly on Veratrine; but by resolving the substance into its element, pro- duces a vellow detonating matter. The alkaloid is entirely dissi- pated by red heat. Tt does not chrystalize, but forms in combi- nation with acids, chrystalizable salts. These latter may be ob- tained by treating the alkaloid with water, acidulated by the acid in question, until they become neutralized, and afterwards evapora- ting. These salts are soluble in water, but their solution are de- composed by heat. It appears that the tartrate is the most eligible of them. The result of Pelletier's analysis is: c. 66.75 equivalent 22 H. = 22. N. 5.04 34 C. =208.08 H. 8.54 6 0. 48. 0. 19.60 N. 14.15 [Wood $ Bache.] The various authors that have given attention to the remedy, and adduced testimony in support of its efficacy, are, so far as 1 have been able to ascertain, named in the following list.: 1. Magendie, Formulaire Pour, etc. Art. Veratrine. 2. Andral, Journal de la Phys. Experimentale, No. 1. 5821. 3. Pelletier & Caventou, Annales de Chymie et de Physique, xiv. 69. 4. Turnbull, on Veratria, London. 5. Bardsley, Hospital Facts and Observations. Manchester, 1830. 6. James Johnson, Medic. Review, vol. 21. 1834. 183 fllg. 7. Brande's Chemical Dictionary. 8. Dr. Bell, in Stoke's Lectures. Art. Neurosis. 9. Jackson, Journal of Pharmacy. 1838. Vol. 3. 186. 10. Pharmacopoeia of the United States of America. Philadel- phia, 1842. 11. Dr. Wood, in Wood & Bache's Dispensatory. 1839. 12. Dunglison's New Remedies. Philadelphia, 1841. 13. Frost's Elements of Materia Medica. Art. Veratrine. 14. Western Journal of Medicine. Lexington, June No. 15- Die Preursische Pharmacopoeia von Dulk. 16. Forcke, Physiologisch therageutische Untersuchungen fiber das Veratria. Hannover, 1834. 17. Ebers on Veratria, in Hufeland's Journal. Dd. 86. 1838. 18. Idem in Caspars Wochenschrift. 19. Riecke. Die Neueren Arzneimittel. New Remedies. The experiments performed on animals, have demonstrated the activity of Veratrine; and its effects on the human organiza- tion are similar. The tincture, which I injected into the nostrils of a dog, excited violent sneezing for half an hour; and the same