Normal human blood serum as a curative agent in hemophilia neonatorum : a preliminary report, with suggestions for its use in other conditions / by John Edgar Welch.

  • Welch, John Edgar.
Date:
1910
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Licence: In copyright

Credit: Normal human blood serum as a curative agent in hemophilia neonatorum : a preliminary report, with suggestions for its use in other conditions / by John Edgar Welch. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    on the eleventh day, 14 c.c. in two doses; total, 76 c.c. in four days (Fio-. 3). The weight of this child ran down steadily until the tenth day” losing altogether 750 grams (H pounds). Two days after receiv- ing the serum it gained 100 grams, then lost 50, after which it held its own and finally gained. Directly after the bleeding began the tem- perature rose to 101.4°, and it did not go below 101° until the bleeding was controlled. This baby was extremely weak and was considered in a serious condition, but was finally discharged from the hospital, with the mother, in good condition. Fio. 3.—Temperature and weight charts of Case III. Case IV.—Third child; male; full term delivery by Cesarean section. On the second day there was slight bleeding from the nose and mouth, and small hemorrhagic spots appeared on the arms and back. The child had embarrassed respiration, attacks of cyanosis and nystagmus. On the third day the hemorrhagic spots increased in size. On the fourth day profuse bleeding from the gums and from the bowels occurred. On the fifth day there was more bleeding from the mouth and rectum and more subcutaneous hemorrhages.