Malarial fever as met with on the Gold Coast / by C. H. Eyles.

Date:
1886
Catalogue details

Licence: Public Domain Mark

Credit: Malarial fever as met with on the Gold Coast / by C. H. Eyles. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    changes in “ the kidney and liver in certain intoxi- cations accompanied by hemoglobinuria and icterus,” and when he says — “ Wenn es bei einem gelbsuch- tigen Thiere sich darum handelte, die Galle in den Harn- und Gallenkanalchen, den Leberzellen, Nier- enepithelien und malpighischen Knaueln an Ort und Stellen zu fixiren, so haben wir die methode ange- wandt, welche,” &c., we must conclude that the condition whose relationship with hemoglobinuria he is investigating is jaundice.1 But he also uses the term icterus to indicate yellowness of the skin and sclerotic, &c., so that in examining the records of his experiments and his conclusions, this dual application of the term has to be borne in mind. When, in speaking of his glycerine injections, he says, in mild intoxication, though haemoglobinaemia existed, the colouring matter of the blood was not excreted by the kidney ; but the intoxication being further pushed, while the liver, spleen, and bone- marrow disposed of some part of the haemoglobin, the remainder appeared in the urine ; and offers as a sufficient explanation for the non-occurrence of “icterusthat the kidney rapidly excreted the haemoglobin; I am able to follow him, if by the term icterus he means absorption jaundice, for it is quite conceivable that the stimulant to the liver being rapidly removed from the circulation, that organ, though urged to increased action, does not 1 To avoid needless repetition and possible misconstruction, I use icterus to denote an-hepatogenous icterus and yellow- tinging of the skin, and jaundice to denote hepatogenous icterus. I