A history of transplantation immunology / Leslie Brent.

  • Brent, Leslie
[1997], ©1997
  • Books
  • Online

About this work


Those entering the field of transplantation are frequently unaware of the topics historical roots and even of the background on which modern discoveries in tolerance, histocompabatibility antigens, and xenotransplantation are based. A History of Transplantation Immunology is an account, written by one of the founding fathers of the field, of how tissue and organ transplantation has become one of the most successful branches of late 20th century medicine. The book helps place the work of contemporary scientists into its proper context and makes fascinating reading for immunologists in all stages of their career. Key Features * Describes landmarks in immunology and places them in historical context * Beautifully written by one of the founding fathers of the field * Portrays the surprising history of events in a colorful and readable manner * Contains biographical sketches of some of the pioneers * Illustrates the development of key ideas in immunology--tolerance, graft rejection, and transplantation * Foreword by Ray Owen.


San Diego : Academic Press, [1997], ©1997.

Physical description

1 online resource (xx, 482 pages) : illustrations


R.D. Owen, Foreword. -- Preface. -- A Note on Nomenclature. -- Landmarks in Immunology. -- The Immunological Basis of Allograft Rejection. -- Blood Transfusion. -- Blood Groups and Hemolytic Disease of the Newborn. -- Immunogenetics: Histocompatibility Antigens--Structure and Function. -- Fetally and Neonatally Induced Immunological Tolerance. -- Immunoregulation--The Search for the Holy Grail. -- Clinical Aspects and Immunosuppression. -- Graft-versus-Host Disease and Bone Marrow Transplantation. -- Xenotransplantation. -- The Mammalian Fetus: Natures (Almost) Perfect Allograft. -- The Interaction Between Immunology, Transplantation, Surgery, and Other Matters. -- Name Index. -- Subject Index.

Bibliographic information

Includes bibliographical references and indexes.



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  • 9780080533995