Annual report on the Medical Research Institute / 1909-.

  • Nigeria. Medical Research Institute.
Date:
[1923]
Catalogue details

Licence: Public Domain Mark

Credit: Annual report on the Medical Research Institute / 1909-. Source: Wellcome Collection.

    16/34 (page 14)
    the rest of the lesion, which showed a darker area in the middle containing a small patch of scar tissue. Weekly intravenous injections of Moogrol have been given since ^ 8/8/23, the first one \ cc., six of 1 cc. and fifteen of 2 cc. . After about two months of treatment slight improvement was apparent at one end of the lesion, but this was balanced by a spread at the other. At the present time, the edges of parts of the lesion are probably somewhat less raised than at first; but, considering the normally changeable nature of leprous patches, the verdict must be that there is no improvement. Case (2) Male, aged twenty-seven years. States seven months a leper. Faint light-coloured macules on back, chest and abdomen, quite difficult to see unless light from right quarter. Weekly intravenous injections of MoogroJ started on 8/8/23. First dose \ cc. followed by five doses 1 cc, followed by five doses 2 cc.” The patient then left prison and disappeared. During treatment the disease progressed regularly and rapidly with the result that the conclusion of treatment found him a well-marked leper. I w7as glad to see him go as I felt I was doing him harm. Case (3) Male, aged thirty years. States eight months a leper. Same type as last case but macules more numerous and more evident. Weekly intravenous injections of Moogrol started 31/10/23. First dose \ cc. second dose 1 cc. followed by eight doses of 2 cc. Up to the present there has been no apparent change, one way or the other. Case (4) Male, aged twenty-five years. States one year a leper. Numerous well-marked macules, type similar to that in Case (1). Started treatment same date as Case (3), dosage the* same, result the same. Dr. A. Gaston reports from Kano, 21/1/24, as follows:— Three lepers are being treated at the present time. They are the anaesthetic type of leprosy. One of them has had the disease for twenty years, and has had seven injections of Moogrol, but not much improvement has been noticed. The other two state that they have had the disease for two years. They are getting weekly injections of Moogrol. They have only had two injections so far and not much improvement has been noticed yet. These three lepers are all prisoners. I find that Moogrol does a lot of good in the anaesthetic form of leprosy which is the only form I have treated with this drug. After six injections I found that the anaesthetic patches had almost completely disappeared and the patients felt much better. Some of them had a slight reaction accompanied by a slight rise in tempera¬ ture and a little induration around the seat of injection, but this soon passed off. Dr. W. E. S. Digby reports, 5/1/24, from Maiduguri. Six lepers suffering from mixed leprosy but with the nodular form more predomi¬ nant, were treated with Moogrol injections, commencing 20th Septem¬ ber, 1923. Their names were :— (1) Mustafa Zavami. (2) Momadu Wanzam. (3) Mallam Hashiim (4) Momadu Mandara. (5) Osuman. (6) Momadu Arimi. The injections were given intramuscularly in the gluteal region, increasing by 1 cc. each week till, on October 25th, each was receiving 6 cc. There was marked improvement in the nodules of (1) who subsequently died 21st December from Broncho-pneumonia. A more marked improvement was noted in the nodules of (2), who refused further treatment after 13th December. In the case of (3) running sores and ulcers dried and healed up, but further treatment was refused after 13th December. In the cases (4), (5) and (6/r no improvement was noticed, but each individual wras emphatic in saying his general health