An introduction to pathology and morbid anatomy / by T. Henry Green.

Date:
1884
Catalogue details

Licence: Public Domain Mark

Credit: An introduction to pathology and morbid anatomy / by T. Henry Green. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    experiments. These have been successfully carried out by Bockbardt.* He injected a fourth cultivation into the urethra of a general paralytic, and produced a puru- lent discharge. The man died of pneumonia ten days later, and an examination of the urethra led Bockhardt to believe that the cocci probably pass through the epithe- lium into the lymphatics of the fossa navicularis, where they excite lively inflammation. They enter into white corpuscles, and pass with them into blood-vessels, where they die ; or they come away in the pus. Pneumonia.—Klebs described a micrococcus as pre- sent in pneumonia,t and was confirmed by Koch J and Friedlander§ who demonstrated the constant pre- sence of the organisms in great numbers in the early stages, not only in the exudation, but also in the lym- phatics of the lung. Friedlanderjl now states that he has cultivated the coccus in blood-serum and gela- tinised meat-infusion and on potato. Diffused in distiUed water and injected into the lung and pleura of rabbits, they produced no effects ; but thirty-two mice died with- out exception, and generaUy in eighteen to twenty hours. The lungs were very red and almost universally sohd, and the spleen was enlarged; both organs contained the characteristic cocci, which were present in considerable numbers in the blood, and in enormous numbers m fluid which occupied the pleura. Guinea-pigs were more refractory to the poison, and only one dog of five suffered. . Inhalation-experiments were made by spraying water charged with cocci for five minutes into the cages of mice*^; three of ten developed pneumonia. The effect of chill was not excluded. . Sitz. Bericht d. Phys. Med. GeseU. Wm-zburg: 1882. t Arch. f. Exp. Path., iv. J Mitth. a. d. k. Gesimdh. 1881. s Virch. Arch., vol. 87. , , , II Portschritte d. Med.; abstract in British MedxcalJoumal, p.