The castration effect

The usefulness of eunuchs

Early Assyrian and Chinese civilisations transposed this knowledge to humans: boys born in poverty would be castrated and sent to work under the yoke of the state in the imperial household. (In China, both penis and testicles were removed – these ‘three treasures’ were pickled in a jar, brought out for special occasions, and buried with the eunuch.) Eunuchs were often taller, sometimes stronger than average, and were frequently employed as the core of an imperial guard. They could work in the imperial harem without fear that they’d cuckold the emperor.

When Alexander the Great conquered Persia he was struck by the utility of such eunuch slaves, and adopted the custom – eunuchs were also considered sexually desirable. The Romans copied it from the Greeks: the Emperor Nero had a eunuch called Sporus (whom he dressed as a woman, and married) and the Emperor Domitian had a favourite eunuch called Earinus.

More: The perceived dangers of male masturbation.

There’s usually an element of voyeurism in the Roman accounts, a curiosity about ambiguous gender and genitalia that’s still visible in media coverage of the phenomenon today. Eunuchs were high-class slaves, the most expensive in the market; in losing testicles they were believed to have lost family loyalty and to have become faithful only to their masters and to the empire.

Around the time that Christianity began to spread into the Roman Empire there was already a cult of a eunuch god called Attis, who was celebrated in springtime and believed to have died then been resurrected after three days. His priests committed self-castration in honour of a fertility goddess, and they did it on the hill in Rome where Vatican City sits now.

The practice survived the Christianisation of the Roman Empire: one of the early Church fathers, Origen, is famous for committing self-castration. Castration continued in Byzantium (where gelded boys were trained as choristers) and into the 20th-century Russian Orthodox church, where the skoptsy sect encouraged self-castration as late as the 1920s.

St Paul’s advice that women should keep quiet in church was taken to its logical conclusion during the Italian Renaissance: God’s glory was sung in soprano by castrated men from the mid-1500s. The Jesuit Tommaso Tamburini, active in the early 17th century, sanctioned castration only “provided there is no mortal danger to life and that it is not done without the boy’s consent”.

How much choice they had in the matter is hard to assess, though reports throughout the 17th and 18th centuries describe boys ‘pleading’ for the honour of being castrated, to bring both prestige and financial security to their families. The complex, high-pitched melodies for which castrati were most in demand by the Vatican were those sung around Easter week – the same time of year that the priests of Attis celebrated castration.

The Vatican didn’t ban the castration of boys for its choirs until the late 19th century, and the last castrato of the Sistine Chapel, Alessandro Moreschi, died in 1922. But 20 years before he died, with his voice already fading in quality, he made a series of recordings for the Gramophone and Typewriter Company, which would become His Master’s Voice or HMV. You can find the recordings online, Moreschi’s voice a wavering, ghostly soprano that makes every song an elegy.

A case of prostate cancer

The comedian Billy Connolly once joked that he’d reached an age when doctors had become uninterested in his balls and had begun showing greater interest in his rectum. The median age for testicular cancer is around 34; for prostate cancer it’s nearer 72. To have your prostate gland checked manually you have to lie on one side, knees pulled up to your chest, while a doctor puts a gloved finger in through your anus – the size and consistency of the prostate can be assessed through the thin bowel wall.

Prostate cancer is common: among my local patient population of almost 4,000, there are several new diagnoses a year. Alex Sinclair was one of them: a 62-year-old builder, muscular and stoical, bald, with a beard so dense and black it was as if the lower half of his face was eclipsed.

He told me he was divorced, and hinted at a dynamic sex life; his children had long ago grown up and moved away. He came to clinic wearing his overalls. “I used to get up once or twice a night to pee,” he told me, “but now it can be five or six times. I wake up exhausted.” There were times he found himself standing at the toilet for a full minute before urine began to trickle out. “I prefer not to see doctors,” he said. “But I couldn’t put it off any more.”

We worked through a questionnaire called the ‘International Prostate Symptom Score’, which asks for a rating of one to five across a series of questions, from how often you have had the sense that you haven’t emptied your bladder to how often you have to strain to initiate urine flow: Alex scored an impressive 22.

I took a blood sample from his arm to examine levels of a substance specific to the prostate – this ‘PSA test’ varies broadly with prostate size, and can on occasion flag up cancer. I asked if I could do a rectal examination up on the couch. “I’ve heard about these,” he said with resignation, standing up to unzip his overalls. “If you must.”

Alex’s prostate was huge, jutting back from its position under the bladder and indenting his rectum. On one side of the crease down the middle of the gland I felt a firmer, discrete lump, like a pebble lodged in tarmac.

“Well, that’s why you’ve been struggling,” I told him. “Your prostate is so large, urine can hardly squeeze through it.” Alex stood up and started pulling up his overalls. “I’d like you to see one of the specialists,” I added, then caught and held his eye. “They’ll want to check tiny pieces of the gland under a microscope.”

His actions slowed as he took in this information. Then he asked carefully: “How do they get the pieces out?”

“They’ll pass a very fine needle in through your anus, and through the bowel wall.” I was hoping to reassure, but wondered if perhaps I was making his anxiety worse. “Your prostate gets bigger the longer it’s been exposed to the testosterone in your body – so the longer you’ve lived, the bigger your prostate grows. You’re not alone – it’s quite common to start getting problems around your age.”

“Is it the same thing as cancer?” he asked, pulling up his zip and reaching for his hat.

I waited a couple of moments, until again his gaze swung back towards me. “Just as every man’s prostate grows the longer he’s lived, they say every man gets prostate cancer if he lives long enough. But in most men it grows slowly, and never causes bother.”

“How will I know if it’s going to cause bother with me?”

Living with hormone treatment

The urologists confirmed it: Alex had prostate cancer. What’s more, it had spread, and so removing his prostate gland to eliminate the tumour wasn’t an option. The first step to improving his quality of life was to widen the urinary passage through the prostate, or “bore it out” as Alex put it (builders have a useful store of analogies when thinking about the body and its failings).

I had assisted in these operations as a junior doctor: a patient was laid anaesthetised on their back, legs in stirrups, while a narrow instrument with a camera inside it was advanced down through the penis and into the bladder. It was always an amazement to watch the procedure, the camera exploring an unseen, barely credible world of pink tunnels and embankments, delicately veined and whorled with contours.

Once into the prostate, a wire loop emerged from the instrument, which, when heated up by an electric current, could simultaneously peel away and cauterise the tissue that had been blocking the urine’s flow. It took a few days for the bleeding to settle down – days in which Alex had to stay in hospital with a wide-bore catheter draining the bladder.

Following the procedure Alex’s urine was flowing, but his cancer was too far advanced to be eliminated. I started him on injections to shut down the production of testosterone in the testes, as well as hormone blockers. Plans were made for radiotherapy at the local hospital.

I reviewed him a couple of weeks after the first injection. His interest in sex had collapsed, his skin felt hot and dry, his urine heavy and stinging. “I’ve never been much of a worrier,” he told me, “but I’m getting uptight about everything these days. And I can’t watch a film without blubbing like a baby.”

He wanted to continue working, but found his muscles ached after even minimal exercise, and he was losing much of his strength. These were all symptoms that could be put down to the loss of testosterone, rather than to the cancer. “I used to lift four sheets of plasterboard no problem,” he told me, “but I think I’ll be lucky if I can manage two.”

Over subsequent weeks his testicles shrank, and though he didn’t lose the density of his beard, his skin took on a pink, delicate sheen, as if it were becoming more fragile.

“Have you had enough?” I asked him one day, after he’d detailed all the side effects that were troubling him. “Do you want to stop the treatment?”

“Not if it’s doing me good,” he replied. “If it’s keeping down the cancer, for me at least – it’s worth it.”

Alex still attends my clinic every twelve weeks for the injections that wither his testicles but slow the growth of his tumour. A pragmatist by nature, he sees the exchange as a reasonable compromise: “I’m lucky to be here,” he says, as he loosens his belt for the injections, which, for their size, have to be given into the largest muscle in the body – the buttock.

After the initial shock of the treatment his libido returned, slowly, and one day he told me he had a new girlfriend. “Her eyes are wide open,” he said, “she knows I might not be around for ever.” I told him just to let me know if he wanted to try medication for impotence, but he just winked. “No need,” he said, “I’ve just got to use a bit more imagination than I used to.”