Wellcome uses cookies.

Read our policy
Wellcome Collection homepage
All
Stories
Images
Catalogue
Events
368 results
  • Four poisonous plants: crowfoot (Ranunculus alpestris), fly agaric fungus (Amanita muscaria), foxglove (Digitalis purpurea) and hellebore (Helleborus niger) Coloured engraving by J. Johnstone.
  • Four poisonous plants: hemlock (Conium maculatum), henbane (Hyoscyamus niger), opium lettuce (Lactuca virosa) and autumn crocus (Colchicum autumnale). Coloured engraving by J. Johnstone.
  • Four poisonous plants: fool's parsley (Aethusa cynapium), cuckoo pint (Arum maculatum), white bryony (Bryonia dioica) and greater celandine (Chelidonium majus). Coloured engraving by J. Johnstone, 1855.
  • Four poisonous plants: monk's hood (Aconitum napellus), deadly nightshade (Atropa belladonna), woody nightshade (Solanum dulcamara) and thorn-apple (Datura stramonium) Coloured engraving by J. Johnstone, 1855.
  • Hyacinthoides non-scripta (L.) Chouard ex Rothm. Asparagaceae Bluebell. Perennial bulbous plant. Distribution W. Europe to N. Portugal. Seed and plants from wild stock are protected in England and Wales and all trade in them is prohibited, despite their abundance. All parts of the plant are poisonous and the sap can cause dermatitis. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Eranthis hyemalis Salisb. Ranunculaceae Winter Aconite Distribution: Europe. The reason it was called Winter aconite and linked to Aconitum napellus as being just as poisonous is because plants were classified according to leaf shape in the 16th century. L'Obel's Stirpium adversaria nova (1571) and Plantarum seu stirpium historia (1576) (with a full page illustration on page 384 showing Eranthis and Aconitum together) along with the knowledge that related plants have similar medical properties caused the belief that Eranthis are as poisonous as Aconitum. They are both in Ranunculaceae and while Eranthis (like all Ranunculaceae)is toxic if eaten, it does not contain the same chemicals as Aconitum. Caesalpino (Ekphrasis, 1616) pointed out the error in classifying according to leaf shape and recommended flower shape. It contains pharmacologically interesting chemicals such as khellin, also present in Ammi visnaga. This is a vasodilator but quite toxic, but can be converted into khellin analogues such as sodium cromoglicate – used as a prophylaxis against asthma attacks – and amiodarone which has anti-arrhythmia actions so is used for atrial fibrillation and other arrhythmias. It is endangered and protected in the wild (Croatia) because of over-collecting for horticulture. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Eranthis hyemalis Salisb. Ranunculaceae Winter Aconite Distribution: Europe. The reason it was called Winter aconite and linked to Aconitum napellus as being just as poisonous is because plants were classified according to leaf shape in the 16th century. L'Obel's 'Stirpium adversaria nova' published in 1571 and 'Plantarum seu stirpium historia' published 1576 (with a full page illustration on page 384 showing Eranthis and Aconitum together) along with the knowledge that related plants have similar medical properties caused the belief that Eranthis are as poisonous as Aconitum. They are both in Ranunculaceae and while Eranthis (like all Ranunculaceae) is toxic if eaten, it does not contain the same chemicals as Aconitum. Caesalpino (Ekphrasis, 1616) pointed out the error in classifying according to leaf shape and recommended flower shape. It contains pharmacologically interesting chemicals such as khellin, also present in Ammi visnaga. This is a vasodilator but quite toxic, which can be converted into khellin analogues such as sodium cromoglicate – used as a prophylaxis against asthma attacks – and amiodarone which has anti-arrhythmia actions so is used for atrial fibrillation and other arrhythmias. It is endangered and protected in the wild (Croatia) because of over-collecting for horticulture. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Aconitum carmichaelii Debeaux. Ranunculaceae. Chinese aconite, Chinese wolfsbane, Carmichael's monkshood. Herbaceous perennial. Distribution C. to W. China to N. America. Named for Dr J.R. Carmichael (d. 1877), English physician, plant collector and Protestant missionary from 1862-1877 in Guangdong and Shandong, China initially in Canton. He aided Francis Forbes to collect plants for Kew. Aconitum plants are so poisonous that Theophrastus states that death was the punishment for possessing them. Aconitine is the poison and was used - from Aconitum ferox - in the 'curry murder' in London in 2009. It causes respiratory paralysis, bradycardia (slowing of the pulse), cardiac arrhythmias, tingling, sweating, gastric cramps, diarrhoea and death, both by ingestion and by absorption through the mucous membranes and the skin. Despite this it is widely used in Chinese herbal medicine. It is a restricted herbal medicine which can only be dispensed by a herbal practitioner for external use following a one-to-one consultation, or by prescription from a registered doctor or dentist (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Adonis vernalis L. Ranunculaceae. Pheasant's eye, the golden flowered spring (or vernal) Adonis, is named in memory of Adonis, the Greek god of plants, who disappeared into the earth in the winter and reappeared in the spring. The flowers were said to have sprung from his blood when he was gored to death by a wild boar, but this plant must have been the blood red Adonis aestivalis, the summer Adonis. Distribution: Eurasia to Spain and Sweden. Gerard (1633) recommends it for renal stone and intestinal colic. Lewis & Elvin Lewis (2003) note it is poisonous, containing cardiac glycosides (adonitoxin, cymarin, K-strophanthin) and flavonoids. The UK Medicines and Healthcare Products Regulatory Agency (MHRA)) bans its use for ingestion 'no dose permitted' but allow it to be prescribed by a herbal practitioner on a one-to-one consultation. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Paris quadrifolia L. Trilliaceae Herb Paris Distribution: Europe and temperate Asia. This dramatic plant was known as Herb Paris or one-berry. Because of the shape of the four leaves, resembling a Burgundian cross or a true love-knot, it was also known as Herb True Love. Prosaically, the name ‘Paris’ stems from the Latin ‘pars’ meaning ‘parts’ referring to the four equal leaves, and not to the French capital or the lover of Helen of Troy. Sixteenth century herbalists such as Fuchs, who calls it Aconitum pardalianches which means leopard’s bane, and Lobel who calls it Solanum tetraphyllum, attributed the poisonous properties of Aconitum to it. The latter, called monkshood and wolfsbane, are well known as poisonous garden plants. Gerard (1633), however, reports that Lobel fed it to animals and it did them no harm, and caused the recovery of a dog poisoned deliberately with arsenic and mercury, while another dog, which did not receive Herb Paris, died. It was recommended thereafter as an antidote to poisons. Coles (1657) wrote 'Herb Paris is exceedingly cold, wherupon it is proved to represse the rage and force of any Poyson, Humour , or Inflammation.' Because of its 'cold' property it was good for swellings of 'the Privy parts' (where presumably hot passions were thought to lie), to heal ulcers, cure poisoning, plague, procure sleep (the berries) and cure colic. Through the concept of the Doctrine of Signatures, the black berry represented an eye, so oil distilled from it was known as Anima oculorum, the soul of the eye, and 'effectual for all the disease of the eye'. Linnaeus (1782) listed it as treating 'Convulsions, Mania, Bubones, Pleurisy, Opththalmia', but modern authors report the berry to be toxic. That one poison acted as an antidote to another was a common, if incorrect, belief in the days of herbal medicine. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Astrantia maxima Pall. Apiaceae. Large masterwort. The botanical name Astrantia is a corruption of the old apothecaries’ name for this plant, Magistrantia “masterwort”, implying its suitability for use only by adepts in herbalism. Probably mildly poisonous. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Poison primula (Primula obconica): flowering plant. Chromolithograph, c. 1897, after H. Moon.
  • Skimmia japonica Thunb. Rutaceae 'Rubella' Distribution: China, Japan and E. Asia. The genus name is derived from the Japanese word shikimi (Stearn, 1994). All parts of the plant are poisonous, containing skimmianin. It is said to cause vomiting and, if eaten in large quantities, cardiac arrest. (Duke, 1985) Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Gloriosa superba L. Colchicaceae Gloriosa lily. Gloriosa rothschildiana is now a synonym. Climbing plant. Distribution: Southern Africa to Asia. National flower of Zimbabwe, state flower of Tamil Nadu. Contains colchicine which is poisonous, teratogenic and used for treating gout, Familial Mediterranean fever and Behcet's disease. Its toxicity limits its use as a anti-cancer agent. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Gloriosa superba L. Colchicaceae Gloriosa lily. Gloriosa rothschildiana is now a synonym. Climbing plant. Distribution: Southern Africa to Asia. National flower of Zimbabwe, state flower of Tamil Nadu. Contains colchicine which is poisonous, teratogenic and used for treating gout, Familial Mediterranean fever and Behcet's disease. Its toxicity limits its use as a anti-cancer agent. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Atropa belladonna L. Solanaceae. Deadly nightshade. Dwale. Morella, Solatrum, Hound's berries, Uva lupina, Cucubalus, Solanum lethale. Atropa derives from Atropos the oldest of the three Fates of Greek mythology who cut the thread of Life (her sisters Clotho and Lachesis spun and measured the thread, respectively). belladonna, literally, means 'beautiful lady' and was the Italian name for it. Folklore has it that Italian ladies put drops from the plant or the fruits in their eyes to make themselves doe-eyed, myopic and beautiful. However, this is not supported by the 16th and 17th century literature, where no mention is ever made of dilated pupils (or any of the effects of parasympathetic blockade). Tournefort (1719) says 'The Italians named this plant Belladonna, which in their language signifies a beautiful woman, because the ladies use it much in the composition of their Fucus [rouge or deceit or cosmetic] or face paint.' Parkinson says that the Italian ladies use the distilled juice as a fucus '... peradventure [perhaps] to take away their high colour and make them looke paler.' I think it more likely that they absorbed atropine through their skin and were slightly 'stoned' and disinhibited, which made them beautiful ladies in the eyes of Italian males. Distribution: Europe, North Africa, western Asia. Culpeper (1650) writes: 'Solanum. Nightshade: very cold and dry, binding … dangerous given inwardly … outwardly it helps the shingles, St Antonie's Fire [erysipelas] and other hot inflammation.' Most of the 16th, 17th and 18th century herbals recommend it topically for breast cancers. Poisonous plants were regarded as 'cold' plants as an excess of them caused death and the body became cold. They were regarded as opposing the hot humour which kept us warm and alive. Poultices of Belladonna leaves are still recommended for muscle strain in cyclists, by herbalists. Gerard (1633) writes that it: 'causeth sleep, troubleth the mind, bringeth madnesse if a few of the berries be inwardly taken, but if more be taken they also kill...'. He was also aware that the alkaloids could be absorbed through the skin for he notes that a poultice of the leaves applied to the forehead, induces sleep, and relieves headache. The whole plant contains the anticholinergic alkaloid atropine, which blocks the peripheral actions of acetylcholine in the parasympathetic nervous system. Atropine is a racemic mixture of d- and l- hyoscyamine. Atropine, dropped into the eyes, blocks the acetylcholine receptors of the pupil so it no longer constricts on exposure to bright light - so enabling an ophthalmologist to examine the retina with an ophthalmoscope. Atropine speeds up the heart rate, reduces salivation and sweating, reduces gut motility, inhibits the vertigo of sea sickness, and is used to block the acetylcholine receptors to prevent the effects of organophosphorous and other nerve gas poisons. It is still has important uses in medicine. Atropine poisoning takes three or for days to wear off, and the hallucinations experienced by its use are described as unpleasant. We have to be content with 'madness', 'frenzie' and 'idle and vain imaginations' in the early herbals to describe the hallucinations of atropine and related alkaloids as the word 'hallucination' in the sense of a perception for which there is no external stimulus, was not used in English until 1646 (Sir T. Browne, 1646). It is a restricted herbal medicine which can only be sold in premises which are registered pharmacies and by or under the supervision of a pharmacist (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Ornithogalum umbellatum L. Hyacinthaceae Star of Bethlehem, Grass lily. Distribution: Central Europe, SW Asia, NW Africa. All parts are poisonous, especially the bulbs. The toxin is a cardiac glycoside with effects similar to digoxin, vomiting, cardiac irregularities and death in humans and livestock. Only used for decoration by Native Americans (it is a non-native plant that has escaped into the wild from cultivation) and called Sleepydick (Moerman, 1998). One of its toxins is Convallotoxin, also present in Lily of the Valley, Convallaria majalis. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Rudbeckia triloba L. Asteraceae Orange Cone flower. Herbaceous perennial. Distribution: North America. It is named for Olof Rudbeck, father (1630–1702) and son (1660–1740). Olof Rudbeck the Elder was professor of medicine at Uppsala University, and established a botanic garden there. He was the discoverer of the human lymphatic system. His son succeeded his father as professor of medicine, and one of his students was Carl Linnaeus (1707–88) who named the genus Rudbeckia after him and his father. It is a plant which is poisonous to cattle, sheep and pigs with no medicinal uses. Austin (1974) discusses R. hirta, also regarded as a toxic plant. It was used externally by the Cherokee to bathe sores and snakebites and made into a tea for treating diarrhoea. The Seminoles used it for headaches and fever and the Miccosukee for sunstroke and headache. The Cherokee and the Iroquois used it to treat intestinal worms Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Illicium verum Hook.f. Illiciaceae Chinese Star Anise Distribution: China. Illicium anisatum Japanese Star Anise. Distribution Japan. Illicium verum is used as a spice in Asian cooking and for Star Anise tea. The distilled oil is added to cough mixture used by children. Introduced to Europe in 1588 (Pharmacographia Indica, 1890). Illicium anisatum syn. religiosum, has been confused with it (Lindley, 1838, Bentley 1861) but is poisonous and was used to make incense in Japanese and Chinese temples. It was called Skimi by Kaempfer. The seed pods of both species contain shikimic acid (the name being derived from the Japanese word for the plant - shi-kimi) from which Tamiflu, the antiviral drug was synthesised. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Nigella sativa L. Ranunculaceae Love-in-the-mist, Black Cumin, Nutmeg flower, Roman Coriander. Distribution: SW Asia. Culpeper (1650) writes: ‘Nigella seeds, boyled in oil, and the forehead anointed with it, ease pains in the head, take away leprosie, itch, scurf, and helps scald-heads, inwardly taken they expel worms, they provoke urine and the terms, help difficulty of breathing: the smoke of them (being burned) drives away serpents and venomous beasts.’ The seeds are used as a spice, but as might be expected as a member of the family Ranunculaceae, the buttercups, the plant contains a highly poisonous glycoside, in this case called melanthin. The amount of toxicity present in spices is clearly insufficient to cause problems when used as such. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Nigella sativa L. Ranunculaceae Love-in-the-mist, Black Cumin, Nutmeg flower, Roman Coriander. Distribution: SW Asia. Culpeper (1650) writes: ‘Nigella seeds, boyled in oil, and the forehead anointed with it, ease pains in the head, take away leprosie, itch, scurf, and helps scald-heads, inwardly taken they expel worms, they provoke urine and the terms, help difficulty of breathing: the smoke of them (being burned) drives away serpents and venomous beasts.’ The seeds are used as a spice, but as might be expected as a member of the family Ranunculaceae, the buttercups, the plant contains a highly poisonous glycoside, in this case called melanthin. The amount of toxicity present in spices is clearly insufficient to cause problems when used as such. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Solanum atropurpureum Schrank Solanaceae. Purple Devil. Purple-spined Nightshade. Herbaceous perennial. Distribution: Brazil. This ferociously spined plant contains tropane alkaloids, atropine, hyoscyamine and scopolamine. All are anticholinergic and block the acetylcholine mediated actions of the parasympathetic nervous system. While the alkaloids are used in medicine and as an antidote to anticholinergic nerve gas poisons, the plant itself is not used in medicine. Its sharp spines can be irritant. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry Distribution: C & S Europe, W. Asia to Japan Culpeper: In his English Physitian of 1652 writes: Winter Cherry ... are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis of 1618. Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry. Distribution: C & S Europe, W. Asia to Japan Culpeper: In his English Physitian of 1652 writes: Winter Cherry ...are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis of 1618. Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry. Distribution: C & S Europe, W. Asia to Japan Culpeper: In his English Physitian of 1652 writes: Winter Cherry ...are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis (1618). Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry. Distribution: C & S Europe, W. Asia to Japan. Culpeper, in his English Physitian of 1652 writes: Winter Cherry ... are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis of 1618. Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry. Distribution: C & S Europe, W. Asia to Japan Culpeper: In his English Physitian of 1652 writes: Winter Cherry ...are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis of 1618. Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Iris graminea L. Iridaceae Grass-leaved flag. Flower de Luce. Distribution: Central and Southern Europe. This is probably the Iris bulbosa minor sive angustifolia [the lesser bulbed or narrow-leaved Iris], Lesser bulbed Flower de luce of Parkinson (1640). He advised that the properties of all Flag Irises were more or less the same, but says there is no agreement about the properties of the bulbous kinds (such as this plant). Of the Flag Irises, Culpeper (1650) writes that the roots 'resist poison, help shortness of the breath, prove the terms [menstruation]
  • Galega officinalis L. Fabaceae. Goat's Rue. Distribution: Central and Southern Europe, Asia Minor. Culpeper (1650) writes that it ‘... resists poison, kills worms, resists the falling sickness [epilepsy], resisteth the pestilence.’ Galega officinalis contains guanidine which reduces blood sugar by decreasing insulin resistance and inhibiting hepatic gluconeogenesis.. Metformin and Phenformin are drugs for type II diabetes that rely on this group of chemicals, known as biguanidines. Its name gala, meaning milk plus ega meaning 'to bring on', refers to its alleged property of increasing milk yield, and has been used in France to increase milk yield in cows. officinalis refers to its use in the offices of the monks, and is a common specific name for medicinal plants before 1600 and adopted by Linnaeus (1753). The fresh plant tastes of pea pods. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Lathyrus vernus (L.)Bernh. Papilionaceae previously Orobus vernus L. (Linnaeus, 1753) Spring vetchling. Distribution: Europe to Siberia. The seeds of several Lathyrus species are toxic, and when eaten cause a condition called lathyrism. The chemical diaminoproprionic acid in the seeds causes paralysis, spinal cord damage, aortic aneurysm, due to poisoning of mitochondria causing cell death. Occurs where food crops are contaminated by Lathyrus plants or where it is eaten as a 'famine food' when no other food is available. It is the Orobus sylvaticus purpureus vernus of Bauhin (1671) and Orobus sylvaticus angustifolius of Parkinson (1640) - who records that country folk had no uses for it. Photographed in the Medicinal Garden of the Royal College of Physicians, London.