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20 results
  • Epithelioma of the eye on the patient Arthur Howard, the Glasgow Royal Cancer Hospital. Photograph, 1925.
  • Castration resistant prostate cancer, human tissue
  • Veratrum nigrum L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and, when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying-in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum - and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Veratrum album L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum -and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Highly invasive human paediatric brain tumour derived cells
  • Highly invasive human paediatric brain tumour derived cells
  • Highly invasive human paediatric brain tumour derived cells
  • A map of London: showing sites of medical interest in Chelsea and Kensington. Coloured lithograph, 1913.
  • A map of London: showing sites of medical interest in Chelsea and Kensington. Coloured lithograph, 1913.
  • The face of a man suffering from cancer of the tongue, showing diseased tissue on the tongue. Watercolour by C. D'Alton, 1867.
  • Two enlarged images of T-cells one infected with HIV by the Frederick Cancer Research and Development Center. Colour lithograph by Nancy Burson and Kunio Nagashima, 1991.
  • A surgical operation to remove a malignant tumour from a man's left breast and armpit in a Dublin drawing room, 1817. Watercolour, ca 1913, after a watercolour, 1817.
  • A surgical operation to remove a malignant tumour from a man's left breast and armpit in a Dublin drawing room, 1817. Watercolour, ca 1913, after a watercolour, 1817.
  • A surgical operation to remove a malignant tumour from a man's left breast and armpit in a Dublin drawing room, 1817. Watercolour, ca 1913, after a watercolour, 1817.
  • A surgical operation to remove a malignant tumour from a man's left breast and armpit in a Dublin drawing room, 1817. Watercolour, ca 1913, after a watercolour, 1817.
  • William Gordon. Photograph by Heath & Bradnee Ltd.
  • 8th self-portrait.
  • 8th self-portrait.
  • Tropaeolum cv
  • Tropaeolum cv