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295 results
  • The Heidelberg jaw and Steinheim skull showing a heavy supra-orbital torus but the occipital region rounded as in modern man, plate XXII, Human Ancestry From a Genetical Point of View, by R. Ruggle Gates, Harvard University Press, 1948
  • Vicia faba L. Fabaceae. Broad beans, Fava bean. Distribution: N. Africa, SW Asia. Culpeper (1650) writes: 'Fabarum. Of Beans. Of Bean Cods (or Pods as we in Sussex call them) being burned, the ashes are a sovereign remedy for aches in the joints, old bruises, gout and sciaticaes.’ The beans are perfectly edible for the majority, but 1% of Caucasians, predominantly among Greeks, Italians and people from the Eastern Mediterranean regions, have a genetic trait in that they lack the ability to produce the enzyme glucose-6-phosphate dehydrogenase. As a consequence, eating broad beans or even inhaling the pollen, causes a severe haemolytic anaemia a few days later. This condition is known as favism. The whole plant, including the beans, contains levodopa, a precursor of dopamine, and some patients with Parkinsonism report symptomatic improvement after commencing on a diet that contains these beans regularly. A case of neuroleptic malignant-like syndrome (fever, rigidity, autonomic instability, altered consciousness, elevated creatine phosphokinase levels) consequent on abrupt discontinuation of a diet containing plenty of broad beans, has been described in a patient with Parkinsonism. This is usually seen when patients abruptly discontinue L-dopa therapy. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Balanced reciprocal translocation 46,XY,t(2;5). This male has a chromosomal disorder. A chromosome 2 and a chromosome 5 have exchanged segments. The cell still contains a complete complement of
  • Fragile X metaphase spread + nucleus
  • Fragile X metaphase spread + nucleus
  • Fragile X metaphase spread
  • Balanced translocation 45,XY,t(21;21)
  • Balanced translocation 45,XY,t(14;21)
  • Balanced translocation 46,XY,t(4;10)
  • Unbalanced translocation 46,XY,t(14;21)
  • Unbalanced translocation 46,XY,t(13;14)
  • Unbalanced translocation 46,XY,t(21;21)
  • Interphase cells showing pentameric X
  • XYY syndrome karyotype 47,XYY
  • Translocation shown up by cosmid probes
  • Translocation, shown by cosmid probes
  • DiGeorge syndrome - deleted/nondeleted FISH
  • Human metaphase, translocation, cosmid probe
  • Aniridia + translocation, FISH & cosmid prob
  • Leukamia karyotype t(8;14)
  • XYY syndrome karyotype 46,XYY
  • Metaphase, deletion on chromosome 15
  • Familial aniridia deletion shown by cosmid
  • Turner's syndrome karyotype 45,XO. This female lacks the second X chromosome present in the normal karyotype. Symptoms include short stature, neck wbbing, elbow deformity, widely spaced nipples with shield chest, primary amenorrhea, sexual infantilism and sterility. The ovaries are reduced to fibrous streaks. Also known as XO syndrome or ovarian short-stature syndrome.
  • Down syndrome human karyotype 47,XY,+21
  • Triple-X chromosome aberration karyotype
  • Duchenne muscular dystrophy pedigree chart
  • Translocation shown using centromere probes
  • Whole arm translocation, centromere probes
  • Aniridia + deletion, FISH probes