concept

Diagnostic test for Fragile X, using presence (normal) or absence (Fragile X syndrome) of FMR-1 protein. FMR-1 protein expression in blood cells has been made visible with antibodies against the FMR-1 protein. The presence of FMR-1 protein is made visible as red staining. a: red staining in cells of normal individual. b/c: absence of staining in male patient. d: female patient; one cell is showing staining and in the other cell there is an absence of staining - this individual is a carrier.

Foetal cells in amniotic fluid, + colchicine

Chorionic villi explants in culture flask

Abnormal foetal cells in amniotic fluid

Foetal cells from amniotic fluid, colchicine

Fragile X chromosome, various stains

Foetal cells in amniotic fluid, low power LM

Foetal cells from amniotic fluid in culture

Chorionic villi samples in petri dish

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Diagnostic testing

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Foetal cells in amniotic fluid, low power LM

Foetal cells from amniotic fluid in culture

Foetal cells from amniotic fluid, colchicine

Chorionic villi explants in culture flask

Abnormal foetal cells in amniotic fluid